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An Observational Trial for Papillary Thyroid Microcarcinoma in Japanese Patients
TLDR
Comparison of the outcomes of 340 patients with PMC who underwent observation and the prognosis of 1,055 patients who underwent immediate surgery without observation shows papillary microcarcinomas that are not associated with unfavorable features can be candidates for observation regardless of patient background and clinical features.
Patient age is significantly related to the progression of papillary microcarcinoma of the thyroid under observation.
TLDR
Although PTMC in young patients may be more progressive than in older patients, it might not be too late to perform surgery after subclinical PTMC has progressed to clinical disease, regardless of patient age.
Clinicopathologic significance of intrathyroidal epithelial thymoma/carcinoma showing thymus-like differentiation: a collaborative study with Member Institutes of The Japanese Society of Thyroid
TLDR
It is suggested that curative resection followed by radiation therapy may effectively prevent locoregional recurrence and CD5 immunostaining is useful for diagnosing ITET/CASTLE.
Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease.
TLDR
MMI 15 mg/d is suitable for mild and moderate GD, whereas MMI 30 mg/D is advisable for severe cases, and PTU is not recommended for initial use.
BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of patients.
TLDR
There is no evidence that BRAF(V600E) mutation significantly reflects the aggressive characteristics and poor prognosis of patients with papillary carcinoma in Japan.
An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid.
TLDR
The preliminary data suggest that papillary microcarcinomas do not frequently become clinically apparent, and that patients can choose observation while their tumors are not progressing, although they are pathologically multifocal and involve lymph nodes in high incidence.
Usefulness of Thyroglobulin Measurement in Fine-needle Aspiration Biopsy Specimens for Diagnosing Cervical Lymph Node Metastasis in Patients with Papillary Thyroid Cancer
TLDR
Thyroglobulin measurement in fine-needle aspiration biopsy wash-out is thus a useful technique for diagnosing lymph node metastasis of papillary thyroid cancer.
Clinical Significance of Metastasis to the Central Compartment from Papillary Microcarcinoma of the Thyroid
TLDR
For papillary microcarcinoma, US is an insensitive technique for detecting the central node metastasis, the presence of central nodes metastasis is unrelated to DFS of patients, and when performing lobectomy for PMC involving only one lobe, dissection of the central compartment in the contralateral lobe is optional.
Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: International standards guideline statement
TLDR
A review of the literature and cumulative experience of the multidisciplinary International Neural Monitoring Study Group with IONM spanning nearly 15 years confirms there is little uniformity in application of and results from nerve monitoring across different centers and helps identify areas where additional research is necessary.
External branch of the superior laryngeal nerve monitoring during thyroid and parathyroid surgery: International Neural Monitoring Study Group standards guideline statement
TLDR
The hypothesis explored in this review is that the use of a standardized approach to the functional preservation of the EBSLN can be facilitated by application of IONM resulting in improved preservation of voice following thyroidectomy or parathyroidectomy.
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