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- Publications
- Influence
Clathrin- and caveolin-1–independent endocytosis
- Eva-Maria Damm, L. Pelkmans, J. Kartenbeck, A. Mezzacasa, T. Kurzchalia, A. Helenius
- Biology, Medicine
- The Journal of cell biology
- 31 January 2005
Simian Virus 40 (SV40) has been shown to enter host cells by caveolar endocytosis followed by transport via caveosomes to the endoplasmic reticulum (ER). Using a caveolin-1 (cav-1)–deficient cell… Expand
Assembly and trafficking of caveolar domains in the cell
- Akiko Tagawa, A. Mezzacasa, Arnold Hayer, Andrea Longatti, L. Pelkmans, A. Helenius
- Biology, Medicine
- The Journal of cell biology
- 29 August 2005
Using total internal reflection fluorescence microscopy (TIR-FM), fluorescence recovery after photobleaching (FRAP), and other light microscopy techniques, we analyzed the dynamics, the activation,… Expand
Intracellular Assembly and Secretion of Recombinant Subviral Particles from Tick-Borne Encephalitis Virus
- I. Lorenz, J. Kartenbeck, A. Mezzacasa, S. L. Allison, F. Heinz, A. Helenius
- Biology, Medicine
- Journal of Virology
- 1 April 2003
ABSTRACT It is believed that flavivirus assembly occurs by intracellular budding of the nucleocapsid into the lumen of the endoplasmic reticulum (ER). Recombinant expression of tick-borne… Expand
The Transitional ER Defines a Boundary for Quality Control in the Secretion of tsO45 VSV Glycoprotein
- A. Mezzacasa, A. Helenius
- Biology, Medicine
- Traffic
- 1 September 2002
Quality control in the secretory pathway limits forward transport of newly synthesized cargo proteins to those that have acquired their fully folded conformation. To determine which organelles… Expand
The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures.
- S. Hemmi, R. Geertsen, A. Mezzacasa, I. Peter, R. Dummer
- Biology, Medicine
- Human gene therapy
- 1 November 1998
Adenovirus (AdV)-mediated gene expression of immune stimulators represents a valuable in vivo approach for gene therapy of human cancer. The expression level of the therapeutic gene is of crucial… Expand
Effects of organelle shape on fluorescence recovery after photobleaching.
- I. Sbalzarini, A. Mezzacasa, A. Helenius, P. Koumoutsakos
- Materials Science, Medicine
- Biophysical journal
- 1 September 2005
The determination of diffusion coefficients from fluorescence recovery data is often complicated by geometric constraints imposed by the complex shapes of intracellular compartments. To address this… Expand
Comparative analysis of immunocritical melanoma markers in the mouse melanoma cell lines B16, K1735 and S91-M3
- I. Peter, A. Mezzacasa, P. Ledonne, R. Dummer, S. Hemmi
- Biology, Medicine
- Melanoma research
- 1 February 2001
The mouse melanoma cell lines B16, K1735 and Cloudman S91-M3 (and various sublines) are frequently used as melanoma models. Extensive comparative data of their immunological features are not… Expand
Immunotherapy for murine K1735 melanoma: Combinatorial use of recombinant adenovirus expressing CD40L and other immunomodulators
- I. Peter, M. Nawrath, J. Kamarashev, B. Odermatt, A. Mezzacasa, S. Hemmi
- Biology, Medicine
- Cancer Gene Therapy
- 1 July 2002
We have constructed and tested five recombinant adenoviruses (Ads) that express a variety of immunomodulators, including CD40 ligand (CD40L), a potent costimulator of several components of the immune… Expand