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Bgugaine, a pyrrolidine alkaloid from Arisarum vulgare, is a strong hepatotoxin in rat and human liver cell cultures.
Toxicity of bgugaine, a pyrrolidine alkaloid extracted from the tubers of Arisarum vulgare, was studied in three different liver cell culture models: (1) the rat hepatocyte primary culture; (2) aExpand
Essential oil composition and antifungal activity of Melissa officinalis originating from north-Est Morocco, against postharvest phytopathogenic fungi in apples.
To investigate biological control methods against post-harvest phytopathogenic fungi in apples, tests on the antifungal activity of essential oil of Melissa officinalis were carried out. TheExpand
Irnigaine and N-Methylirnigaine, Two New Piperidinol Alkaloids from the Tubers of Arisarum vulgare
Abstract From the tubers of Arisarum vulgare, we have isolated two new toxic piperidinol alkaloids. By 2D COSY NMR spectroscopic methods, their structures were elucidated as follows Irnigaine 3:Expand
Structure of irniine a pyrrolidine alkaloid from arisarum vulgare
A toxic pyrrolidine alkaloid, irniine [1], was isolated from Arisarum vulgare tubers, and its structure was elucidated by 2D COSY spectroscopic methods
Antibacterial activity and virtual screening by molecular docking of lycorine from Pancratium foetidum Pom (Moroccan endemic Amaryllidaceae).
Lycorine is an alkaloid isolated from bulbs of Pancratium foetidum Pom Amaryllidaceae of the genus Lycoris. It has very strong pharmacodynamics properties and biological effects, among others,Expand
Anti-cancer effect of two alkaloids: 2R and 2S-bgugaine on mastocytoma P815 and carcinoma Hep
The 2-alkylpyrrolidine R-bgugaine, a natural alkaloid isolated from tubers of Arisarum vulgare Targ. Tozz. (Araceae), and its isomer S-bgugaine, obtained by an asymmetric synthesis, were examined forExpand
Volatile Components and Antioxidant Effect of Essential Oil of Anthemis mauritiana Maire & Sennen Flowers
The volatile components isolated from flowers of Anthemis mauritiana have been studied. The essential oil was obtained by hydrodistillation and by micro steam distillation and analysis were performedExpand
New pyrazolic compounds as cytotoxic agents
The evaluation of the in vitro cytotoxic properties of two pyrazole compounds: 1-(4-nitrophényl)-3,5-diméthylpyrazole (1) and 1,1′-di(4-nitrophényl)-5,5′-diisopropyl-3,3′-bipyrazole (2) wasExpand
Anticancer effect of three pyrazole derivatives
The evaluation of the cytotoxic properties in vitro of three synthetic tripods containing pyrazole: N,N-bis[(3,5-dimethylpyrazol-1-yl)methyl]aniline (1);Expand