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Isoguanine quartets formed by d(T4isoG4T4): tetraplex identification and stability.
TLDR
The self-aggregation of the oligonucleotide d(T4isoG4T4) is investigated and a tetrameric structure was formed in the presence of sodium ions and shows almost the same chromatographic mobility on ion exchange HPLC as d (T4G4 T4) (2). Expand
Parallel-Stranded Duplex DNA and Self-Assembled Quartet Structures Formed by Isoguanine and Related Bases
Abstract Parallel-stranded (ps) oligonucleotide duplexes are described containing isoguanine-cytosine and/or 5-methylisocytosine-guanine base pairs. A parallel hybrid is also formed whenExpand
Parallel-stranded duplex DNA formed by a new base pair between guanine and 5-aza-7-deazaguanine
Abstract Oligonucleotides containing 5-aza-7-deazaguanine residues have been synthesized. A DNA duplex with parallel strand orientation is assembled by a new base pair between guanine andExpand
5‐Aza‐7‐deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo[1,2‐a]‐1,3,5‐triazine Nucleosides
The base-pairing properties of oligonucleotides containing the anomeric 5-aza-7-deazaguanine 2′-deoxyribonucleosides 1 and 5 are described. The oligonucleotides were prepared by solid-phaseExpand
PARALLEL-STRANDED DNA FORMED BY NEW BASE PAIRS RELATED TO THE ISOGUANINE-CYTOSINE OR ISOCYTOSINE-GUANINE MOTIFS
Abstract Parallel-stranded (ps) oligonucleotide duplexes containing several new base pairs formed between 7-deazaisoguanine and cytosine, 8-aza-7-deaza-isoguanine and cytosine, and 5-aza-7-deazaExpand
Four-Stranded Dna Formed by Isoguanine Quartets: Complex Stoichiometry, Thermal Stability and Resistance Against Exonucleases
TLDR
The iGd-tetrads are more stable with regard to their thermal denaturation and to their resistance against enzymatic phosphodiester hydrolysis than those formed by dG. Expand
Synthesis and application of novel nucleoside phosphonates and phosphoramidites modified at the base moiety.
TLDR
The synthesis of isoguanine oligonucleotides was found to be much more efficient using the 2-O-protected building blocks compared to those without oxygen protection. Expand
The α-d anomer of 5-aza-7-deaza-2′-deoxyguanosine
In the monohydrate of 2-amino-8-(2-deoxy-α-d-erythro-pento­furan­osyl)-8H-imidazo­[1,2-a]­[1,3,5]­triazin-4-one, C10H13N5O4·H2O, denoted (I) or αZd, the conformation of the N-gly­cosyl­ic bond is inExpand
Oligonucleotides Containing Consecutive 2′-Deoxy-Isoguanosine Residues: Synthesis, Parallel Duplex Formation and Identification of a d(T4iG4T4) Tetraplex
Abstract Oligonucleotides containing consecutive 2′-deoxyisoguano-sines were synthesized by using building blocks protected with a diphenylcarb-amoyl residue. Parallel duplexes were formed by iGd-dCExpand
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