A. McCartney

Publications98
h-index30
Citations6,192
Highly Influential Citations236
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Prebiotic effects: metabolic and health benefits
TLDR
The present document has been written by a group of both academic and industry experts and aims to validate and expand the original idea of the prebiotic concept, defined as the selective stimulation of growth and/or activity of one or a limited number of microbial genus(era)/species in the gut microbiota that confer(s) health benefits to the host. Expand
Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children.
TLDR
Strategies to reduce clostridial population levels harboured by ASD patients or to improve their gut microflora profile through dietary modulation may help to alleviate gut disorders common in such patients. Expand
Application of molecular biological methods for studying probiotics and the gut flora
  • A. McCartney
  • Medicine, Biology
  • British Journal of Nutrition
  • 1 September 2002
TLDR
The future of molecular biology in the field of probiotics and the gut flora will, no doubt, stretch to investigations of functionality and activity of the microflora, and/or specific fractions. Expand
Molecular characterisation of the gut microflora of healthy and inflammatory bowel disease cats using fluorescence in situ hybridisation with special reference to Desulfovibrio spp.
TLDR
Modulation of bacterial flora by increasing bifidobacteria and decreasing Desulfovibrio spp. Expand
An In Vitro Study of the Probiotic Potential of a Bile-Salt-Hydrolyzing Lactobacillus fermentum Strain, and Determination of Its Cholesterol-Lowering Properties
TLDR
Results from this in vitro study suggest that L. fermentum KC5b is a candidate probiotic which may affect cholesterol metabolism and specifically the molar proportion of propionate and/or bile salt deconjugation are probably the major mechanism involved in the purported cholesterol-lowering properties of this strain. Expand
Top-down systems biology modeling of host metabotype-microbiome associations in obese rodents.
TLDR
Data suggest a conditional host genetic involvement in selection of the microbial species in each host strain, and that both lean and obese animals could have specific metabolic phenotypes that are linked to their individual microbiomes. Expand
Isolation and characterization of human colonic bacteria able to hydrolyse chlorogenic acid
D. COUTEAU, A.L. McCARTNEY, G.R. GIBSON, G. WILLIAMSON AND C.B. FAULDS. 2001.
Molecular analysis of the composition of the bifidobacterial and lactobacillus microflora of humans
TLDR
Analysis of the composition of the bifidobacterial populations by using ribotyping or pulsed-field gel electrophoresis to differentiate between bacterial strains demonstrated major differences between the subjects. Expand
Physiological and Bifidogenic Effects of Prebiotic Supplements in Infant Formulae
TLDR
Stool consistency and bacterial composition of infants taking SYN1 0.8 g/dL or GOS:FOS–supplemented formula were closer to the breast-fed pattern, while during the first month of life, weight, length, intake, stool characteristics, crying, regurgitation, vomiting, adverse events, and fecal bacterial population counts increased. Expand
Longitudinal investigation of the faecal microbiota of healthy full-term infants using fluorescence in situ hybridization and denaturing gradient gel electrophoresis.
TLDR
Large inter-individual variation was evident within the infant faecal microbiota and its development, even within exclusively formula-fed infants receiving the same diet. Expand
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