• Publications
  • Influence
The Comprehensive Antibiotic Resistance Database
The CARD integrates disparate molecular and sequence data, provides a unique organizing principle in the form of the Antibiotic Resistance Ontology (ARO), and can quickly identify putative antibiotic resistance genes in new unannotated genome sequences. Expand
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobialExpand
Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lamblia
The genome of the eukaryotic protist Giardia lamblia, an important human intestinal parasite, is compact in structure and content, contains few introns or mitochondrial relics, and has simplifiedExpand
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
A new Resistomes & Variants module provides analysis and statistical summary of in silico predicted resistance variants from 82 pathogens and over 100 000 genomes, able to summarize predicted resistance using the information included in CARD, identify trends in AMR mobility and determine previously undescribed and novel resistance variants. Expand
Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish
It is revealed that the majority of zebrafish CYP genes are expressed in embryos, with waves of expression of different sets of genes over the course of development, which provides a foundation for the use ofZebrafish as a model in toxicological, pharmacological and chemical disease research. Expand
IslandViewer 3: more flexible, interactive genomic island discovery, visualization and analysis
Overall, IslandViewer 3 represents a significant new version of this GI analysis software, with features that may make it more broadly useful for general microbial genome analysis and visualization. Expand
A Biogeographical Perspective of the Deep-Sea Hydrothermal Vent Fauna
Hydrothermal vents provide a good testing ground for processes that control patterns in diversity, and faunas on two sides of the Pacific and in the Atlantic have closer relations to each other than to the nearby “normal” deep-sea fauna. Expand
The Giardia genome project database.
The Giardia genome project database provides an online resource for Giardia lamblia (WB strain, clone C6) genome sequence information. The database includes edited single-pass reads, the results ofExpand
Developmental changes in the adhesive disk during Giardia differentiation.
The composition and structure of the disk throughout the life cycle of Giardia lamblia is determined and a new disk protein, SALP-1, is identified, an immunodominant protein related to striated fiber-assemblin (SFA) that is stored within the cyst. Expand
A New Family of Giardial Cysteine-Rich Non-VSP Protein Genes and a Novel Cyst Protein
The data suggest that HCNCp is a novel invariant cyst protein belonging to a new HCMp family that is abundant in the Giardia genome and provide a rich source for developing parasite-specific diagnostic reagents, vaccine candidates, and subjects for further research intoGiardia biology. Expand