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High levels of antibodies against merkel cell polyomavirus identify a subset of patients with merkel cell carcinoma with better clinical outcome.
- A. Touzé, E. Le Bidre, +13 authors P. Coursaget
- MedicineJournal of clinical oncology : official journal…
- 20 April 2011
High titers of MCV antibodies in a much higher proportion of patients with MCC than in controls confirmed the association between MCV infection and MCC and suggested that there are at least two distinct etiologic causes of MCC.
Generation of Merkel Cell Polyomavirus (MCV)-Like Particles and Their Application to Detection of MCV Antibodies
- A. Touzé, Julien Gaitan, +9 authors P. Coursaget
- Biology, MedicineJournal of Clinical Microbiology
- 24 February 2010
To investigate MCV seroprevalence in the general population, three different MCV VP1 genes were expressed in insect cells using recombinant baculoviruses and viruslike particles (VLPs) were obtained with only one of the threeVP1 genes.
Dermatological Spectrum of Hand, Foot and Mouth Disease from Classical to Generalized Exanthema
- T. Hubiche, I. Schuffenecker, +9 authors P. del Giudice
- MedicineThe Pediatric infectious disease journal
- 1 April 2014
Hospitalised children with confirmed HFMD have a clinical spectrum ranging from classical to generalized vesicular exanthema, and CV-A6 is associated with peri-oral rash, which is related to coxsackie virus A6 when there is an atypical rash.
Merkel Cell Polyomavirus Strains in Patients with Merkel Cell Carcinoma
- A. Touzé, Julien Gaitan, +8 authors P. Coursaget
- Biology, MedicineEmerging infectious diseases
- 1 June 2009
This work investigated whether Merkel cell carcinoma patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations and found strains from France and the United States were similar.
Clinical Phenotype of Scabies by Age
There is a specific clinical presentation of scabies in infants and children that seems to vary according to age, taking into account these specificities may be helpful for the early diagnosis and the identification of cases to prevent the propagation of the disease.
CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders
Clinical investigations of the patients carrying CNTN5 or CNTn6 variants showed that they were hypersensitive to sounds and displayed changes in wave latency within the auditory pathway, reinforcing the hypothesis of abnormal neuronal connectivity in the pathophysiology of ASD and shed new light on the genes that increase risk for abnormal sensory perception in ASD.
Sturge‐Weber Syndrome in Patients with Facial Port‐Wine Stain
- M. Piram, G. Lorette, D. Sirinelli, D. Herbreteau, B. Giraudeau, A. Maruani
- MedicinePediatric dermatology
Knowledge of the topography of facial PWS with risk of associated neurological or ocular anomalies allows for early diagnosis of SWS and avoids unnecessary and costly radiography for patients with uncomplicated facial P WS.
Molecular diagnosis of PIK3CA-related overgrowth spectrum (PROS) in 162 patients and recommendations for genetic testing
The data demonstrate the value of ultradeep NGS for molecular diagnosis of PROS, highlight its substantial allelic heterogeneity, and confirm that optimal diagnosis requires fresh skin or surgical samples from affected regions.
Successful treatment of ulcerated haemangioma with propranolol
- M. Naouri, T. Schill, A. Maruani, F. Bross, G. Lorette, J. Rossler
- MedicineJournal of the European Academy of Dermatology…
- 1 September 2010
Ulceration is a frequent complication of proliferating haemangioma and may be a cause of death in patients with this type of cancer.
Patients' acceptance of medical photography in a French adult and paediatric dermatology department: a questionnaire survey
Despite the increasing use of medical photography by dermatologists, no study on patients' perceptions of photography in dermatology has been performed to date.