Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties.
- M. Choudhary, S. Nawaz, A. ur-Rahman
- Chemistry, BiologyBiochemical and Biophysical Research…
- 19 August 2005
Emodinol, ß-Glucuronidase Inhibiting Triterpene from Paeonia Emodi
- N. Riaz, I. Anis, Atta-ur-rahman
- Chemistry
- 1 August 2003
Emodinol, a new oleane type triterpene, has been isolated from the chloroform soluble fraction of Paeonia emodi. The structure 1β, 3β, 23-trihydroxyolean-12-en-28-oic acid 1 has been assigned on the…
Isolation and cholinesterase-inhibition studies of sterols from Haloxylon recurvum.
- E. Ahmed, S. Nawaz, A. Malik, M. Choudhary
- Biology, ChemistryBioorganic & Medicinal Chemistry Letters
- 1 February 2006
Isolation and Enzyme‐Inhibition Studies of the Chemical Constituents from Ajuga bracteosa
- N. Riaz, S. Nawaz, M. Choudhary
- Chemistry, BiologyChemistry and Biodiversity
- 1 January 2007
Lineweaver–Burk, and Dixon plots, and their secondary replots indicated that all compounds exhibit non‐competitive type of inhibition with Ki values in the range of 9.5–35.2, 15.2–36.0, and 11.6–20.5 μM, for lipoxygenase, acetylcholinesterase, and butyrylcholinease, respectively.
Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora
- Sadia Ferheen, Aziz-Ur-Rehman, Rasool Bakhsh Tareen
- ChemistryJournal of Enzyme Inhibition and Medicinal…
- 23 September 2009
New flavanone glucosides A and B have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora and showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active.
Cholinesterase‐Inhibiting Withanolides from Ajuga bracteosa
- N. Riaz, A. Malik, Aziz‐ur‐Rehman, S. Nawaz, Pir Muhammad, M. Choudhary
- ChemistryChemistry and Biodiversity
- 1 September 2004
Three new withanolides have been isolated from the whole plants of Ajuga bracteosa and exhibited evident inhibitory potential against cholinesterase enzymes in a concentration‐dependent fashion.
Isolation and Lipoxygenase‐Inhibition Studies of Phenolic Constituents from Ehretia obtusifolia
- K. Iqbal, S. Nawaz, M. Choudhary
- ChemistryChemistry and Biodiversity
- 1 January 2005
The phenolic compounds methyl 2‐O‐feruloyl‐1a‐O‐vanillactate (1), caffeic anhydride (2), and trans 4‐hydroxycyclohexyl‐2‐O‐p‐coumaroyl β‐D‐glucopyranoside (3) have been isolated from the…
Potent Anti-Platelet Constituents from Centaurea iberica
- A. N. Khan, I. Fatima, H. Rasheed
- ChemistryMolecules
- 28 February 2011
New naturally occurring nitrogenous compounds 1 and 2, along with a new dimeric lignan glucoside 3, have been isolated from the ethyl acetate soluble fraction of Centaurea iberica and all the isolated compounds showed significant platelet aggregation inhibition.
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