• Publications
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Assembly of the Drosophila germ plasm.
  • A. Mahowald
  • Biology, Medicine
  • International review of cytology
  • 2001
The Drosophila melanogaster germ plasm has become the paradigm for understanding both the assembly of a specific cytoplasmic localization during oogenesis and its function. The posterior ooplasm isExpand
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tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster
Developmental analysis of a newly isolated maternal effect grandchildless mutant, tudor (tud), in Drosophila melanogaster indicates that tud+ activity is required during oogenesis for theExpand
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Multiple functions of segment polarity genes in Drosophila.
l(1)dishevelled (l(1)dsh) is a late zygotic lethal mutation that exhibits a rescuable maternal effect lethal phenotype. l(1)dsh/Y embryos, derived from females possessing a homozygous l(1)dshExpand
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Regulation of the vitellogenin receptor during Drosophila melanogaster oogenesis.
In many insects, development of the oocyte arrests temporarily just before vitellogenesis, the period when vitellogenins (yolk proteins) accumulate in the oocyte. Following hormonal and environmentalExpand
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Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division
Adult stem cells often divide asymmetrically to produce one self-renewed stem cell and one differentiating cell, thus maintaining both populations. The asymmetric outcome of stem cell divisions canExpand
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A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis.
Basement membranes (BMs) are specialized extracellular matrices that are essential for epithelial structure and morphogenesis. However, little is known about how BM proteins are delivered to theExpand
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The Drosophila yolkless gene encodes a vitellogenin receptor belonging to the low density lipoprotein receptor superfamily.
Sequence comparisons of vitellogenins from a wide range of organisms have identified regions of similarity not only to each other but also to vertebrate apolipoproteins (e.g. apoB-100 and apoE).Expand
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The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice.
The Drosophila svb/ovo gene gives rise to differentially expressed transcripts encoding a zinc finger protein. svb/ovo has two distinct genetic functions: shavenbaby (svb) is required for properExpand
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In vitro activation of Drosophila eggs.
Mature ovarian eggs of Drosophila can be activated by treatment with hypotonic buffers. Well-fed, 4-day-old virgin flies contain large numbers of partially dehydrated mature eggs. When these eggs areExpand
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A germline-specific gap junction protein required for survival of differentiating early germ cells.
Germ cells require intimate associations and signals from the surrounding somatic cells throughout gametogenesis. The zero population growth (zpg) locus of Drosophila encodes a germline-specific gapExpand
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