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Necrosis of HepG2 cancer cells induced by the vibration of magnetic particles
Experiments of magnetolysis, i.e., destruction of cells induced with magnetic particles (MPs) submitted to the application of a magnetic field, were conducted on HepG2 cancer cells. We herein…
Coupling surface plasmon resonance to mass spectrometry to discover novel protein–protein interactions
- A. Madeira, Elisabeth Öhman, A. Nilsson, B. Sjögren, P. Andrén, P. Svenningsson
- Chemistry, MedicineNature Protocols
- 1 June 2009
This protocol describes the approach to discover protein–protein interactions using the surface plasmon resonance technique coupled to mass spectrometry (MS), which immobilizes a peptide or a protein on a sensor chip and is exposed to brain extracts injected through the surface of the chip by a microfluidic system.
The Joule heating problem in silver nanowire transparent electrodes.
- H. H. Khaligh, L. Xu, +7 authors I. A. Goldthorpe
- Materials Science, MedicineNanotechnology
- 20 September 2017
It is shown that graphene, a commonly used passivation layer for these electrodes, slows nanowire degradation and creates a more uniform surface temperature under current flow, but the graphene does not prevent Joule heating in the nanowires and local points of high temperature ultimately shift the failure mechanism from nanowired degradation to melting of the underlying plastic substrate.
Use of surface plasmon resonance coupled with mass spectrometry reveals an interaction between the voltage-gated sodium channel type X alpha-subunit and caveolin-1.
- E. Ohman, A. Nilsson, A. Madeira, B. Sjögren, P. Andrén, P. Svenningsson
- Chemistry, MedicineJournal of proteome research
- 1 December 2008
It is anticipated that the surface plasmon resonance-mass spectrometry approach utilized in this study will be important for the elucidation of protein-protein network analysis in native tissues including the brain.
Versatile template-directed synthesis of gold nanocages with a predefined number of windows.
The new multi-step synthesis approach reported here also allows the synthesis of rattle-like nanostructures through filling of the nanocages with a guest nano-object, and opens new routes towards the fabrication of hollow nanostructure of high interest for a variety of applications including sensing devices, catalytic reactors and biomedicine.
Increasing Silver Nanowire Network Stability through Small Molecule Passivation
- A. Madeira, Marie Plissonneau, L. Servant, I. A. Goldthorpe, M. Tréguer-Delapierre
- Materials Science, MedicineNanomaterials
- 1 June 2019
It is shown that passivating the nanowire surfaces with small organic molecules of 11-mercaptoundecanoic acid (MUA) does not affect electrode transparency contrary to typical passivation films, and is inexpensive and simple to deposit.
Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression
- A. Madeira, Junfeng Yang, +4 authors P. Svenningsson
- Medicine, BiologyNeurochemistry International
- 1 August 2011
It can be concluded that Cav-1 may play a functional role in neuronal cells by virtue of its physical interaction with alpha-synuclein and regulate alpha synuclein-mediated actions on cell death, processes known to be involved inSynucleinopathies including Parkinson's disease.
Identification of protein-protein interactions by surface plasmon resonance followed by mass spectrometry.
- A. Madeira, E. Vikeved, A. Nilsson, B. Sjögren, P. Andrén, P. Svenningsson
- Chemistry, MedicineCurrent protocols in protein science
- 1 August 2011
This unit describes an approach to discover protein-protein interactions by coupling surface plasmon resonance to mass spectrometry using the Mascot software.
Efficient Passivation of Ag Nanowires with 11‐Mercaptoundecanoic Acid Probed Using In Situ Total‐Internal‐Reflection Surface‐Enhanced Raman Scattering Spectroscopy
- Marie Plissonneau, A. Madeira, +8 authors M. Tréguer-Delapierre
- Materials ScienceChemNanoMat
- 20 February 2019
A promising passivation strategy of one class of Ag nanostructures of high interest for optoelectronics, namely Ag nanowires (AgNWs), with 11‐mercaptoundecanoic acid (MUA) is described. Combining…
Synthesis and Surface Modification of Spindle-Type Magnetic Nanoparticles: Gold Coating and PEG Functionalization
In this paper, we describe the synthesis of gold coated spindle-type iron nanoparticles and its surface modification by a thiolated fluorescently-labelled polyethylene glycol (PEG) polymer. A…