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Congenital Heart Disease in the General Population: Changing Prevalence and Age Distribution
Background— Empirical data on the changing epidemiology of congenital heart disease (CHD) are scant. We determined the prevalence, age distribution, and proportion of adults and children with severe… Expand
Changing mortality in congenital heart disease.
- P. Khairy, R. Ionescu-Ittu, A. Mackie, M. Abrahamowicz, L. Pilote, A. Marelli
- Journal of the American College of Cardiology
- 28 September 2010
OBJECTIVES This study sought to characterize temporal trends in all-cause mortality in patients with congenital heart disease (CHD). BACKGROUND Historically, most deaths in patients with CHD… Expand
Birth prevalence of congenital heart disease.
A Novel Method of Expressing Left Ventricular Mass Relative to Body Size in Children
- B. Foster, A. Mackie, M. Mitsnefes, H. Ali, Silvia Mamber, S. Colan
- 31 October 2007
Background— Left ventricular (LV) hypertrophy (LVH) in children is widely defined as a left ventricular mass index (LVMI, g/m2.7) >95th percentile. However, LVMI increases with decreasing height in… Expand
Truncus arteriosus associated with interrupted aortic arch in 50 neonates: a Congenital Heart Surgeons Society study.
BACKGROUND Patients with both interrupted aortic arch (IAA) and truncus arteriosus (TA) have worse outcomes than those with either lesion in isolation. We determined outcomes and associated factors… Expand
Lifetime Prevalence of Congenital Heart Disease in the General Population From 2000 to 2010
- A. Marelli, Raluca Ionescu-Ittu, A. Mackie, Liming Guo, N. Dendukuri, M. Kaouache
- 26 August 2014
Background— Our objective was to obtain contemporary lifetime estimates of congenital heart disease (CHD) prevalence using population-based data sources up to year 2010. Methods and Results— The… Expand
Specialized Adult Congenital Heart Disease Care: The Impact of Policy on Mortality
Background— Clinical guidelines recommend specialized care for adult congenital heart disease (ACHD) patients. In reality, few patients receive such dedicated care. We sought to examine the impact of… Expand
Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: relationship to exercise capacity, cumulative dose and remodeling
- E. Tham, M. Haykowsky, +6 authors R. Thompson
- Journal of Cardiovascular Magnetic Resonance
- 10 June 2013
BackgroundThe late cardiotoxic effects of anthracycline chemotherapy influence morbidity and mortality in the growing population of childhood cancer survivors. Even with lower anthracycline doses,… Expand
Infective Endocarditis in Children With Congenital Heart Disease: Cumulative Incidence and Predictors
Background— The American Heart Association guidelines for prevention of infective endocarditis (IE) in 2007 reduced the groups of congenital heart disease (CHD) patients for whom antibiotic… Expand
Normal rotational, torsion and untwisting data in children, adolescents and young adults.
- K. Takahashi, Ghassan Al Naami, Richard Thompson, A. Inage, A. Mackie, J. Smallhorn
- Journal of the American Society of…
- 1 March 2010
BACKGROUND Left ventricular (LV) torsion and untwisting are important components of LV performance, but there is little information on the effect of age, particularly in younger populations. … Expand