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Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells.
The ethyl acetate extract from the fermentation broth of an actinomycete strain, identified as Streptomyces scabrisporus isolated from soil of Kashmir Himalayas - India, exhibited significantExpand
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Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
ABSTRACT Imbalance in production and clearance of amyloid beta (Aβ) is the primary reason for its deposition in Alzheimer disease. Macroautophagy/autophagy is one of the important mechanisms forExpand
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Isolation and characterization of three benzylisoquinoline alkaloids from Thalictrum minus L. and their antibacterial activity against bovine mastitis.
ETHNO-PHARMACOLOGICAL RELEVANCE The roots of Thalictrum minus are traditionally used in the treatment of inflammation and infectious diseases such as bovine mastitis. However, there are no reportsExpand
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Bovine mastitis: An appraisal of its alternative herbal cure.
Bovine mastitis is globally recognized as the most common and costly disease affecting dairy herds. The disease causes huge financial losses to dairy industries by reduced yield and milk quality,Expand
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Antimicrobial investigation of selected soil actinomycetes isolated from unexplored regions of Kashmir Himalayas, India.
The aim of the present study was to isolate and evaluate the antimicrobial potential of soil actinomycetes of Kashmir Himalayas. The secondary metabolites of actinomycetes are the prominent source ofExpand
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Streptomyces puniceus strain AS13., Production, characterization and evaluation of bioactive metabolites: A new face of dinactin as an antitumor antibiotic.
A highly active actinobacterial strain isolated from untapped areas of Northwestern Himalayas and characterised as Streptomyces puniceus strain AS13 by 16S rRNA gene sequencing was selected forExpand
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In vitro evaluation of dinactin, a potent microbial metabolite against Mycobacterium tuberculosis.
Current long duration treatment options and the emergence of drug resistance in tuberculosis (TB) have led to renewed interest in discovery of novel anti-tubercular agents or the scaffolds exhibitingExpand
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Isolation, characterization and HPLC quantification of compounds from Aquilegia fragrans Benth: Their in vitro antibacterial activities against bovine mastitis pathogens.
ETHNO-PHARMACOLOGICAL RELEVANCE The underground parts of Aquilegia fragrans are traditionally used for the treatment of wounds and various inflammatory diseases like bovine mastitis. However, thereExpand
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Evaluating the in vitro antituberculosis, antibacterial and antioxidant potential of fungal endophytes isolated from Glycyrrhiza glabra L.
Endophytes, especially from medicinal plants and those from biodiversity rich ecoregions synthesize important bioactive molecules. The aim of the present study was to isolate and characterize theExpand
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Chemoprofile and functional diversity of fungal and bacterial endophytes and role of ecofactors – A review
Endophytes represent a hidden world within plants. Almost all plants that are studied harbor one or more endophytes, which help their host to survive against pathogens and changing adverseExpand
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