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Antibacterial activity of some African medicinal plants used traditionally against infectious diseases
Context: Plants are known to play a crucial role in African traditional medicine for the treatment of infection diseases. Objectives: To investigate the claimed antimicrobial properties of plantsExpand
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Bioactive compounds from the African medicinal plant Cleistochlamys kirkii as resistance modifiers in bacteria
Cleistochlamys kirkii (Benth) Oliv. (Annonaceae) is a medicinal plant traditionally used in Mozambique to treat infectious diseases. The aim of this study was to find resistance modifiers in C.Expand
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Evaluation of the Antiviral and Antimicrobial Activities of Triterpenes Isolated from Euphorbia segetalis
A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3β-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3β,24-diol (2),Expand
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A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein.
A new sesquiterpene-coumarin ether (5'beta,9'alpha,10'alpha)-7-0-(3alpha-methoxy-8'(12')-drimen-11'-yl)-scopoletin, designated driportlandin (1) and a new abietane quinoid diterpeneExpand
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The effects of jatrophane derivatives on the reversion of MDR1- and MRP-mediated multidrug resistance in the MDA-MB-231 (HTB-26) cell line.
Multidrug resistance (MDR) of cancer cells can be the result of a variety of mechanisms that are not completely understood. One of the most significant among them concerns altered membrane transportExpand
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Colon adenocarcinoma multidrug resistance reverted by Euphorbia diterpenes: structure-activity relationships and pharmacophore modeling.
Multidrug resistance (MDR) is a limiting step on the success of cancer chemotherapy. The drug efflux mediated by P-gp (Pglycoprotein) is one of the best studied mechanisms of MDR. This paper focusesExpand
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Antimicrobial activity of selected extracts from Hakea salicifolia and H. sericeae (Proteaceae) against Staphylococcus aureus multiresistant strains
Abstract The antimicrobial activity of several plant extracts obtained from aerial parts of two invasive plants, Hakea sericeae and Hakea salicifolia , was evaluated against both Gram-positive andExpand
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Lavandula stoechas subsp. luisieri and L. pedunculata - phytochemical study, micromorphology and histochemistry Lavandula stoechas subsp. luisieri e L. pedunculata - estudo fitoquímico,
Extracts of different polarities were obtained from plants of Lavandula stoechas subsp. luisieri and Lavandula pedunculata collected in the Center and Southwest Portugal. In order to have an idea onExpand
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Effect of cycloartanes on reversal of multidrug resistance and apoptosis induction on mouse lymphoma cells.
The ability of fifteen cycloartanes, isolated from Euphorbia species, to reverse multidrug resistance (MDR) and apoptosis induction in L5178Y mouse lymphoma cells, including its multidrug-resistantExpand
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Euphorbia and Momordica metabolites for overcoming multidrug resistance
Multidrug resistance (MDR) is the major obstacle for cancer chemotherapy. MDR is a multifactorial phenomenon that can result from several mechanisms, including an increased drug efflux, due toExpand
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