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Age-related changes in fatty acid profile and locomotor activity rhythms in Nothobranchius korthausae
The life cycle of Nothobranchius korthausae, a Cyprinodontiformes fish, was studied in our laboratory to characterise the ageing process. Some morphological changes, such as spine curvature, skinExpand
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Analysis of the coding sequences of clownfish reveals molecular convergence in the evolution of lifespan
BackgroundStandard evolutionary theories of aging postulate that reduced extrinsic mortality leads to evolution of longevity. Clownfishes of the genus Amphiprion live in a symbiotic relationship withExpand
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The clock is ticking. Ageing of the circadian system: From physiology to cell cycle.
The circadian system is the responsible to organise the internal temporal order in relation to the environment of every process of the organisms producing the circadian rhythms. These rhythms have aExpand
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Age-related changes in mitochondrial membrane composition of Nothobranchius rachovii.
Mitochondrial membrane composition may be a critical factor in the mechanisms of the aging process by influencing the propagation of reactions involved in mitochondrial function during periods ofExpand
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Nothobranchius as a model for aging studies. A review.
In recent decades, the increase in human longevity has made it increasingly important to expand our knowledge on aging. To accomplish this, the use of animal models is essential, with the most commonExpand
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Changes in mitochondrial membrane composition and oxidative status during rapid growth, maturation and aging in zebrafish, Danio rerio.
Considering membranes and membrane components as possible pacemakers of the main processes taking place inside mitochondria, changes in phospholipids or fatty acids could play a central role linkingExpand
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Rest-activity circadian rhythms in aged Nothobranchius korthausae. The effects of melatonin
Adult (48-week-old) and senescent (72-week-old) individually-kept Nothobranchius korthausae were used as experimental subjects to characterise circadian system (CS) function and age-related changesExpand
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Circadian monitoring as an aging predictor
The ageing process is associated with sleep and circadian rhythm (SCR) frailty, as well as greater sensitivity to chronodisruption. This is essentially due to reduced day/night contrast, decreasedExpand
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Circadian activity rhythms during the last days of Nothobranchius rachovii’s life: A descriptive model of circadian system breakdown
Several studies have been performed to identify age-related changes in the circadian system (CS) but the impairment of the CS and its chronodisruption at the end of an organism life have not beenExpand
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