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Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster.
Heterochromatin in Drosophila has unusual genetic, cytological and molecular properties. Highly repeated DNA sequences (satellites) are the principal component of heterochromatin. Using probes from… Expand
Horizontal transmission, vertical inactivation, and stochastic loss of mariner-like transposable elements.
Horizontal transmission has been well documented as a major mechanism for the dissemination of mariner-like elements (MLEs) among species. Less well understood are mechanisms that limit vertical… Expand
Multiplicity of satellite DNA sequences in Drosophila melanogaster.
Three Drosophila melanogaster satellite DNAs (1.672, 1.686, and 1.705 g/ml in CsCl), each containing a simple sequence repeated in tandem, were cloned in pBR322 as small fragments about 500 base… Expand
Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation.
Genetic studies of the mariner transposable element Mos1 have revealed two novel types of regulatory mechanisms. In one mechanism, overproduction of the wild-type transposase reduces the overall… Expand
Modern thoughts on an ancyent marinere: function, evolution, regulation.
The mariner/Tc1 superfamily of transposable elements is one of the most diverse and widespread Class II transposable elements. Within the larger assemblage, the mariner-like elements (MLEs) and the… Expand
Mutations in the mariner transposase: the D,D(35)E consensus sequence is nonfunctional.
- A. Lohe, D. D. de Aguiar, D. Hartl
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 18 February 1997
Genetic analysis of eukaryote transposases and comparison with their prokaryote counterparts have been greatly hindered by difficulty in isolating mutations. We describe a simple eye-color screen… Expand
There are two mechanisms of achiasmate segregation in Drosophila females, one of which requires heterochromatic homology.
There are numerous examples of the regular segregation of achiasmate chromosomes at meiosis I in Drosophila melanogaster females. Classically, the choice of achiasmate segregational partners has been… Expand
Fine mapping of satellite DNA sequences along the Y chromosome of Drosophila melanogaster: relationships between satellite sequences and fertility factors.
The entirely heterochromatic Y chromosome of Drosophila melanogaster contains a series of simple sequence satellite DNAs which together account for about 80% of its length. Molecular cloning of the… Expand
Identical satellite DNA sequences in sibling species of Drosophila.
The evolution of simple satellite DNAs was examined by DNA-DNA hybridization of ten Drosophila melanogaster satellite sequences to DNAs of the sibling species, Drosophila simulans and Drosophila… Expand
What restricts the activity of mariner-like transposable elements.
A number of mechanisms have recently been described that might be important in restricting the level of activity of mariner-like transposable elements (MLEs) in natural populations. These mechanisms… Expand