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Extremely thermophilic microorganisms as metabolic engineering platforms for production of fuels and industrial chemicals
Enzymes from extremely thermophilic microorganisms have been of technological interest for some time because of their ability to catalyze reactions of industrial significance at elevatedExpand
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Bioprocessing analysis of Pyrococcus furiosus strains engineered for CO2‐based 3‐hydroxypropionate production
Metabolically engineered strains of the hyperthermophile Pyrococcus furiosus (Topt 95–100°C), designed to produce 3‐hydroxypropionate (3HP) from maltose and CO2 using enzymes from the MetallosphaeraExpand
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Ancillary contributions of heterologous biotin protein ligase and carbonic anhydrase for CO2 incorporation into 3‐hydroxypropionate by metabolically engineered Pyrococcus furiosus
Acetyl‐Coenzyme A carboxylase (ACC), malonyl‐CoA reductase (MCR), and malonic semialdehyde reductase (MRS) convert HCO3− and acetyl‐CoA into 3‐hydroxypropionate (3HP) in theExpand
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Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea.
The 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle fixes CO2 in extremely thermoacidophilic archaea and holds promise for metabolic engineering because of its thermostability and potentiallyExpand
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Production of lignofuels and electrofuels by extremely thermophilic microbes
Extreme thermophiles are microorganisms that grow optimally at elevated temperatures (≥ 70°C). They could play an important role in the emerging renewable energy landscape by exploiting thermophilyExpand
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Angular Measurement Error Due to Different Measuring Devices
Background: Angular measurements are commonly used in orthopaedic surgery. No study has addressed measurement variability due to the measurement device itself. It was the purpose of this study toExpand
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Determinants of Sulfur Chemolithoautotrophy in the Extremely Thermoacidophilic Sulfolobales.
Species in the archaeal order Sulfolobales thrive in hot acid and exhibit remarkable metabolic diversity. Some species are chemolithoautotrophic, obtaining energy through oxidation of inorganicExpand
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A hybrid synthetic pathway for butanol production by a hyperthermophilic microbe.
Biologically produced alcohols are of great current interest for renewable solvents and liquid transportation fuels. While bioethanol is now produced on a massive scale, butanol has superior fuelExpand
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Putting violence in context.
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