• Publications
  • Influence
Human hyaluronidases: electrophoretic multiple forms in somatic tissues and body fluids. Evidence for conserved hyaluronidase potential N-glycosylation sites in different mammalian species.
Some properties of the multiple forms of human hyaluronidases in somatic tissues and in body fluids were investigated. Liver and placenta exhibited seven hyaluronidase forms when analyzedExpand
  • 28
  • 3
Cell migration-the role of integrin glycosylation.
BACKGROUND Cell migration is an essential process in organ homeostasis, in inflammation, and also in metastasis, the main cause of death from cancer. The extracellular matrix (ECM) serves as theExpand
  • 137
  • 2
Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients
Galectin-3 (Gal-3) is a member of the &bgr;-galactoside-binding lectins family and has been implicated in angiogenesis, tumor invasion, and metastatic process in vitro and in vivo. As we showedExpand
  • 49
  • 2
Differences of alpha3beta1 integrin glycans from different human bladder cell lines.
Expression as well as properties of integrins are altered upon transformation. Cell adhesion regulated by integrins is modulated by glycosylation, one of the most frequent biochemical alterationExpand
  • 23
  • 2
Diversified β-2-adrenergic Receptor Expression and Action in Melanoma Cells.
BACKGROUND/AIM Growing evidence links stress hormones with development and progression of various cancer types. The aim of this study was to assess susceptibility of cutaneous and uveal melanomaExpand
  • 3
  • 2
Tetraspanin CD151 Regulates Glycosylation of α3β1 Integrin*
The tetraspanin CD151 forms a stoichiometric complex with integrin α3β1 and regulates its endocytosis. We observed that down-regulation of CD151 in various epithelial cell lines changed glycosylationExpand
  • 64
  • 1
Identification of proteins bearing beta1-6 branched N-glycans in human melanoma cell lines from different progression stages by tandem mass spectrometry analysis.
The common structural alterations in the cell-surface glycoproteins concern the highly elevated expression of tri- and tetra-antennary beta1-6-N-acetylglucosamine (beta1-6 GlcNAc) bearing N-glycans,Expand
  • 39
  • 1
Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines.
Changes in the expression of integrins and cadherins might contribute to the progression, invasion and metastasis of transitional cell cancer of the bladder and of melanomas. The expression of alpha5Expand
  • 41
  • 1
Characterisation of alpha3beta1 and alpha(v)beta3 integrin N-oligosaccharides in metastatic melanoma WM9 and WM239 cell lines.
It is well documented that glycan synthesis is altered in some pathological processes, including cancer. The most frequently observed alterations during tumourigenesis are extensive expression ofExpand
  • 28
  • 1
β1-6 branching of cell surface glycoproteins may contribute to uveal melanoma progression by up-regulating cell motility
Purpose This study investigated the influence of integrin expression as well as the oligosaccharide structure of surface N-glycoproteins on cell behavior of two primary uveal (92–1 and Mel202) andExpand
  • 29
  • 1