Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin
- C. Vieira, S. Fetzer, S. Manzini
- Biology, MedicineNaunyn-Schmiedeberg's Archives of Pharmacology
- 1 August 2001
Ricinoleic acid possesses capsaicin-like dual pro-inflammatory and anti-inflammatory properties which are observed upon acute and repeated application, respectively.
MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK2 receptor antagonist
- R. Catalioto, M. Criscuoli, C. Maggi
- Biology, ChemistryBritish Journal of Pharmacology
- 1 January 1998
The affinities (potency and selectivity) showed by MEN”11420 for different tachykinin receptors, measured either in binding or in functional bioassays, were similar to those shown by the parent compound, MEN’10627.
Effect of ricinoleic acid in acute and subchronic experimental models of inflammation.
- C. Vieira, S. Evangelista, R. Cirillo, A. Lippi, C. Maggi, S. Manzini
- Medicine, BiologyMediators of Inflammation
- 2000
RA may be seen as a new capsaicin-like, non-pungent anti-inflammatory agent suitable for peripheral application, particularly if given by the intradermal route.
Tachykinin receptors and intestinal motility
- C. Maggi, R. Catalioto, A. Giachetti
- Chemistry
- 1 June 1997
La substance P (SP) et la neurokinine A (NKA) sont synthetisees par les motoneurones cholinergiques enteriques qui projettent vers les muscles circulaires et longitudinaux de l'intestin de mammifere.…
Tachykinin receptors and intestinal motility.
- C. Maggi, R. Catalioto, A. Giachetti
- BiologyCanadian Journal of Physiology and Pharmacology
- 1997
Substance P (SP) and neurokinin A (NKA) are synthesized by enteric cholinergic motorneurons that project to the longitudinal and circular muscle of the mammalian intestine. Thus, acetylcholine, SP,…
Effect of the aromatase inhibitor, MEN 11066, on growth of two different MCF-7 sublines.
- C. Palma, M. Criscuoli, A. Lippi, M. Muratori, S. Mauro, C. Maggi
- Biology, ChemistryEuropean Journal of Pharmacology
- 8 December 2000
Effect of rociverine on P450-dependent monooxygenases and its N-deethylation metabolism in rat liver microsomes.
- S. Menicagli, A. Lippi, M. Criscuoli, P. Gervasi
- Biology, ChemistryBiochemical Pharmacology
- 9 March 1993
The metabolism of carbamazepine in humans: steric course of the enzymatic hydrolysis of the 10,11-epoxide.
- G. Bellucci, G. Berti, C. Chiappe, A. Lippi, F. Marioni
- Chemistry, BiologyJournal of Medicinal Chemistry
- 1 May 1987
This finding confirms the pronounced enantioselectivity of the microsomal epoxide hydrolase toward meso and racemic substrates, but is in contrast with the prevalent formation of (R,R)-diols in most other known cases of enzymatic hydrolysis of epoxides.
Structure activity relationship of epoxides: different mutagenicity of the two diastereoisomeric 3-bromo-1,2-epoxycyclohexanes.
- G. Bellucci, A. Lippi, F. Marioni, L. Citti, P. Gervasi, G. Turchi
- Chemistry, BiologyChemico-Biological Interactions
- 1 September 1984
Depolarization evoked co-release of tachykinins from enteric nerves in the guinea-pig proximal colon
- A. Lippi, P. Santicioli, M. Criscuoli, C. Maggi
- BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
- 10 March 1998
It is concluded that SP and NKA are evenly co-released in response to graded depolarization of enteric nerves in the guinea-pig colon, and the specialization of tachykininergic transmission observed in functional studies does not originate at the prejunctional level.
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