A. Limat

Publications65
h-index22
Citations1,708
Highly Influential Citations20
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Co-culture of human keratinocytes on post-mitotic human dermal fibroblast feeder cells: production of large amounts of interleukin 6.
A large synthesis of human IL-6 was demonstrated in co-cultures of human keratinocytes on post-mitotic human dermal fibroblast (HDF) feeder layers. Immunoreactive IL-1 beta could be detected in the… Expand
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Intracellular Localization of Keratinocyte Fas Ligand Explains Lack of Cytolytic Activity under Physiological Conditions*
Acquired Fas ligand (FasL)-mediated cytolytic activity of human keratinocytes causes the massive keratinocyte cell death that occurs during toxic epidermal necrolysis, a deadly adverse drug eruption.… Expand
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Inhibition of protease activity can lead to neurite extension in neuroblastoma cells.
Publisher Summary Neurite extension is one of the first morphological steps in neuronal differentiation. A study on the nature and the regulation of the biochemical events involved in this phenomenon… Expand
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Post-mitotic human dermal fibroblasts efficiently support the growth of human follicular keratinocytes.
For growth at low seeding densities, keratinocytes isolated from human tissues like epidermis or hair follicles are dependent on mesenchyme-derived feeder cells such as the 3T3-cell employed so far.… Expand
  • 117
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Endogeneously regulated site-specific differentiation of human palmar skin keratinocytes in organotypic cocultures and in nude mouse transplants.
  • A. Limat, E Stockhammer, +6 authors T. Hunziker
  • Biology, Medicine
  • European journal of cell biology
  • 1 March 1996
Palmar and plantar epidermis is characterized by specific features such as the development of a striking lucidum, a very thick stratum corneum, prominent rete ridges and the unique expression of… Expand
  • 23
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Serial cultivation of single keratinocytes from the outer root sheath of human scalp hair follicles.
  • A. Limat, F. Noser
  • Biology, Medicine
  • The Journal of investigative dermatology
  • 1 October 1986
A method for the isolation of outer root sheath keratinocytes from plucked human hair follicles and for their subsequent cultivation has been developed. The selective trypsinization of outer root… Expand
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Acute generalized exanthematous pustulosis: role of cytotoxic T cells in pustule formation.
Extensive formation of nonfollicular sterile pustules on erythematous background combined with fever and peripheral blood leukocytosis are the characteristics of acute generalized exanthematous… Expand
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Autoantibodies from a patient with paraneoplastic pemphigus bind periplakin, a novel member of the plakin family.
  • 55
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Differential expression of connexins during stratification of human keratinocytes.
To assess whether gap junctions and connexins change during keratinocyte differentiation, we have studied epidermal equivalents obtained in organotypic cultures of keratinocytes from the outer root… Expand
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Large increase of Langerhans cells in human skin lymph derived from irritant contact dermatitis
In order to monitor the kinetics of Langerhans cells in the afferent lymph during contact dermatitis, a superficial peripheral lymph vessel draining the skin of the upper and medial part of the foot… Expand
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