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- Publications
- Influence
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- C. Anderson, G. Boucher, +110 authors J. Rioux
- Biology, Medicine
- Nature Genetics
- 6 February 2011
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-wide association… Expand
Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease.
- F. Ruemmele, G. Veres, +30 authors D. Turner
- Medicine
- Journal of Crohn's & colitis
- 1 October 2014
Children and adolescents with Crohn's disease (CD) present often with a more complicated disease course compared to adult patients. In addition, the potential impact of CD on growth, pubertal and… Expand
ESPGHAN Revised Porto Criteria for the Diagnosis of Inflammatory Bowel Disease in Children and Adolescents
- A. Levine, S. Koletzko, +17 authors D. Wilson
- Medicine
- Journal of pediatric gastroenterology and…
- 1 November 2013
Background: The diagnosis of pediatric-onset inflammatory bowel disease (PIBD) can be challenging in choosing the most informative diagnostic tests and correctly classifying PIBD into its different… Expand
Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification
- A. Levine, A. Griffiths, +9 authors J. Hyams
- Medicine
- Inflammatory bowel diseases
- 1 June 2011
Background: Crohn's disease and ulcerative colitis are complex disorders with some shared and many unique predisposing genes. Accurate phenotype classification is essential in determining the utility… Expand
Common variants at five new loci associated with early-onset inflammatory bowel disease
- M. Imielinski, R. Baldassano, +46 authors H. Hakonarson
- Biology, Medicine
- Nature Genetics
- 1 December 2009
The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis are common causes of morbidity in children and young adults in the western world. Here we report the results of a… Expand
Levels of drug and antidrug antibodies are associated with outcome of interventions after loss of response to infliximab or adalimumab.
- H. Yanai, Lev Lichtenstein, +14 authors S. Ben-Horin
- Medicine
- Clinical gastroenterology and hepatology : the…
- 1 March 2015
BACKGROUND & AIMS
There is controversy about whether levels of anti-tumor necrosis factor (TNF) and antidrug antibodies (ADAs) are accurate determinants of loss of response to therapy. We analyzed… Expand
Food allergy is a matter of geography after all: sesame as a major cause of severe IgE‐mediated food allergic reactions among infants and young children in Israel
Objective: To determine the prevalence, importance, and the order of frequency of IgE‐mediated food allergens among infants and young children in Israel.
Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases
- A. Levine, R. Sigall Boneh, E. Wine
- Medicine
- Gut
- 18 May 2018
Recent advances in basic and clinical science over the last 3 years have dramatically altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked increase in… Expand
Appraisal of the Pediatric Crohn's Disease Activity Index on Four Prospectively Collected Datasets: Recommended Cutoff Values and Clinimetric Properties
- Dan Turner, A. Griffiths, +9 authors A. Levine
- Medicine
- The American Journal of Gastroenterology
- 1 September 2010
OBJECTIVES:The Pediatric Crohn's Disease Activity Index (PCDAI) is the outcome measure of choice in clinical trials of pediatric Crohn's disease. The aim of this study was to provide knowledge on its… Expand
Consensus for Managing Acute Severe Ulcerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN
- Dan Turner, S. Travis, +16 authors R. Russell
- Medicine
- The American Journal of Gastroenterology
- 1 April 2011
OBJECTIVES:Acute severe ulcerative colitis (ASC) is a potentially life-threatening disease. We aimed to formulate guidelines for managing ASC in children based on systematic review of the literature… Expand