• Publications
  • Influence
The effect of aerobic metabolism on the inducible glycerol dehydrogenase of Aerobacter aerogenes.
Aerobacter aerogenes strain 1033 can utilize glycerol as sole source of carbon and energy under aerobic and anaerobic conditions (2). With the aid of isotope enantiomorphs of glycerol1-V it could beExpand
  • 48
  • 1
ACTION OF A HISTIDINE ANALOGUE, 1,2,4-TRIAZOLE-3-ALANINE, IN SALMONELLA TYPHIMURIUM.
Levin, Alfred P. (The Johns Hopkins University, Baltimore, Md.), and Philip E. Hartman. Action of a histidine analogue, 1,2,4-triazole-3-alanine, in Salmonella typhimurium. J. Bacteriol. 86:820-828.Expand
  • 41
Inhibition of enzyme formation following infection of Escherichia coli with phage T2r.
SUMMARY: The synthesis of aspartate carbamyl transferase (ureidosuccinic synthetase), of dihydroorotic dehydrogenase and of alkaline phosphatase by a uracil-requiring strain of Escherichia coli, whenExpand
  • 14
  • PDF
Enzyme synthesis in guanine-starved cells.
Whether or not the concomitant synthesis of ribonucleic acid is essential for the formation of enzymes has been the subject of a great deal of speculation. It is well known that purine or pyrimidineExpand
  • 10
  • PDF
Inactivation of cholinesterase by compounds related to neostigmine.
Compounds 3113 CT and 3152 CT, which are chemically related to neostigmine, exhibit an I 50 (concentration necessary to produce 50 per cent inactivation) against erythrocyte cholinesterase, underExpand
  • 7
Demonstration of an effector site for the enzyme inosine 5'-phosphate dehydrogenase.
  • 9
The effect of purines on the formation of two enzymes involved in purine biosynthesis.
In many instances the end product of a sequence of biosynthetic reactions inhibits the formation of enzymes responsible for these reactions. Such “negative feedback” effects have been observed inExpand
  • 24
Some comparative kinetic data on the enzyme imidazoleacetol phosphate:L-glutamate aminotransferase derived from mutant strains of Salmonella typhimurium.
Abstract A comparison was made of the kinetic properties of the aminotransferase derived from two his mutants and coded for by the C gene of the histidine operon. The data presented show that, inExpand
  • 7
Aminotransferase from a deletion mutant in the histidine operon.
The imidazolylacetolphosphate:l-glutamate aminotransferase from the deletion mutant hisHB22 has been partially characterized. Although genetic studies have not yet shown the deletion to involve theExpand
  • 3
Alteration of repression in purine biosynthesis.
  • A. Levin
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 18 April 1967
Abstract Back mutations from a strain of Salmonella typhimurium with a defect in inosine 5′-phosphate dehydrogenase (EC 1.2.1.14) have been isolated and the content of the enzyme in these cells hasExpand
  • 4