• Publications
  • Influence
Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes
TLDR
A new class introduced in the CAZy database is named “Auxiliary Activities” in order to accommodate a range of enzyme mechanisms and substrates related to lignocellulose conversion and provides a better coverage of the full extent of the lignin degradation machinery. Expand
Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists
TLDR
Convergent evolution of the mycorrhizal habit in fungi occurred via the repeated evolution of a 'symbiosis toolkit', with reduced numbers of PCWDEs and lineage-specific suites of myCorrhiza-induced genes. Expand
Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi
TLDR
The results indicate that the prevailing paradigm of white rot vs. brown rot does not capture the diversity of fungal wood decay mechanisms, and suggest a continuum rather than a dichotomy between the white-rot and brown-rot modes of wood decay. Expand
Genome sequence of the model mushroom Schizophyllum commune
TLDR
The wood-degrading fungus Schizophyllum commune is both a genetically tractable model for studying mushroom development and a likely source of enzymes capable of efficient degradation of lignocellulosic biomass. Expand
Genome sequence of the model medicinal mushroom Ganoderma lucidum
TLDR
The sequence analysis reveals an impressive array of genes encoding cytochrome P450s (CYPs), transporters and regulatory proteins that cooperate in secondary metabolism, making this organism a potential model system for the study of secondary metabolic pathways and their regulation in medicinal fungi. Expand
Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen
TLDR
It is established that Gc is heterothallic, and evidence for repeat-induced point mutation is reported, and insights are reported into how Gc tolerates conifer-defense chemicals, including oleoresin terpenoids, as they colonize a host tree. Expand
The Genomes of the Fungal Plant Pathogens Cladosporium fulvum and Dothistroma septosporum Reveal Adaptation to Different Hosts and Lifestyles But Also Signatures of Common Ancestry
TLDR
Comparison of the genomes of the Dothideomycete fungal plant pathogens suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization, and gene regulation. Expand
Culture of previously uncultured members of the human gut microbiota by culturomics
TLDR
It is shown that the use of culturomics allows the culture of organisms corresponding to sequences previously not assigned, which doubles the number of species isolated at least once from the human gut. Expand
Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France
TLDR
Administration of the HCQ+AZ combination before COVID-19 complications occur is safe and associated with very low fatality rate in patients, retrospectively report on 1061 SARS-CoV-2 positive tested patients. Expand
GPR50 is the mammalian ortholog of Mel1c: Evidence of rapid evolution in mammals
TLDR
There are only three members in the melatonin receptor subfamily with one of them undergoing rapid evolution from fishes and birds to mammals, and GPR50 is the ortholog of the high affinity Mel1c receptor. Expand
...
1
2
3
4
5
...