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Collagen made of extended -chains, procollagen, in genetically-defective dermatosparaxic calves.
Collagen has been extracted from the skin of dermatosparaxic calves and fractionated by acrylamide-gel electrophoresis and CM-cellulose chromatography. This collagen contains in large proportion twoExpand
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Procollagen peptidase: an enzyme excising the coordination peptides of procollagen.
A heritable connective tissue disorder of cattle, dermatosparaxis, is characterized by an extreme fragility of the skin and the presence of additional peptides at the N-terminal extremities of theExpand
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Cardiovascular effects of moderate normovolaemic haemodilution during enflurane–nitrous oxide anaesthesia in man
The cardiovascular effects of mild normovolaemic haemodilution during enflurane–nitrous oxide anaesthesia were studied in 20 patients with normal cardiac function before, during and after total hipExpand
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Electronoptical studies of procollagen from the skin of dermatosparaxic calves
Recent evidence indicates that precursors of collagen can be detected in collagen synthesizing tissues [l-3] . The a-chains of this precursor molecule “procollagen” have a higher molecular weight andExpand
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Calf tendon procollagen peptidase: its purification and endopeptidase mode of action.
The procollagen peptidase activity of calf tendon has been purified. The enzyme has a high degree of specificity for native procollagen and converts both pro alpha1 and alpha2, to alpha1 and alpha2,Expand
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Arterial Reactivity, Blood Pressure, and Plasma Levels of Atrial Natriuretic Peptides in Normotensive and Hypertensive Rats: Effects of Acute and Chronic Administration of Atriopeptin III
We compared acute and chronic effects of atriopeptin III in normotensive and spontaneously hypertensive rats. Atriopeptin III relaxed isolated aortae and intrarenal microarteries but not coronary andExpand
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Phenothiazines inhibit copper and endothelial cell-induced peroxidation of low density lipoprotein. A comparative study with probucol, butylated hydroxytoluene and vitamin E.
The effect of two phenothiazines, chlorpromazine (CPZ) and trifluoperazine (TFP) on the copper and endothelial cell-induced peroxidation of low density lipoprotein (LDL) has been studied and comparedExpand
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Calcium antagonists prevent monocyte and endothelial cell-induced modification of low density lipoproteins.
Low density lipoprotein (LDL) incubated in the presence of the calcium antagonists verapamil, nifedipine and flunarizine were more resistant than control LDL to human monocyte- or endothelialExpand
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Daflon 500 mg depresses bradykinin-ischemia-induced microvascular leakage of FITC dextran in rat cremaster muscle.
We studied the in vivo effects of Daflon 500 mg on transvascular movement of macromolecules induced by bradykinin (BK) and ischemia. The experimental preparation involved the rat cremaster muscle.Expand
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Determination of sorbitol and galactitol at the nanogram level in biological samples by high-performance liquid chromatography.
Aldose reductase is an enzyme that plays an important role in diabetic complications such as cataract and neuropathy. The best way to estimate the enzymatic activity of this enzyme in vivo consistsExpand
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