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Comparing Families of Dynamic Causal Models
A combination of two further approaches: family level inference and Bayesian model averaging within families to provide inferences about parameters that are independent of further assumptions about model structure are proposed.
Lesion identification using unified segmentation-normalisation models and fuzzy clustering
Spatial Normalization of Brain Images with Focal Lesions Using Cost Function Masking
The results suggest that cost-function masking is superior to the standard approach to this problem, which is affine-only normalization; it is proposed that it should be used routinely for normalizations of brains with focal lesions.
Defining a left-lateralized response specific to intelligible speech using fMRI.
The results demonstrate that there are neural responses to intelligible speech along the length of the left lateral temporal neocortex, although the precise processing roles of the anterior and posterior regions cannot be determined from this study.
Speech Facilitation by Left Inferior Frontal Cortex Stimulation
The left superior temporal gyrus is a shared substrate for auditory short-term memory and speech comprehension: evidence from 210 patients with stroke
High-resolution structural magnetic resonance images from 210 stroke patients are analysed and it is found that the structural integrity of a posterior region of the superior temporal gyrus and sulcus predicted auditory short-term memory capacity, even when performance on a range of other measures was factored out.
The Cortical Dynamics of Intelligible Speech
- A. Leff, T. Schofield, K. E. Stephan, J. Crinion, Karl J. Friston, C. Price
- BiologyThe Journal of Neuroscience
- 3 December 2008
Dynamic causal modeling of functional magnetic resonance imaging responses and Bayesian model selection was applied to investigate, for the first time, experimentally induced changes in coupling among three key multimodal regions that were activated by intelligible speech and found the best model was a “forward” system that was driven by auditory inputs into the pSTS.
Cognitive Control and the Salience Network: An Investigation of Error Processing and Effective Connectivity
- T. Ham, A. Leff, X. de Boissezon, Anna Joffe, D. Sharp
- Psychology, BiologyThe Journal of Neuroscience
- 17 April 2013
It is concluded that the aRI, not the d ACC, drives the SN after errors on an attentionally demanding task, and that a change in the effective connectivity of the dACC is associated with behavioral adaptation after errors.
Spatial normalization of lesioned brains: Performance evaluation and impact on fMRI analyses
Computer-assisted therapy for medication-resistant auditory hallucinations: proof-of-concept study
- J. Leff, G. Williams, M. Huckvale, Maurice Arbuthnot, A. Leff
- Psychology, MedicineBritish Journal of Psychiatry
- 11 February 2013
Avatar therapy represents a promising treatment for medication-resistant auditory hallucinations and a computerised system that enables the patient to create an avatar of their persecutor.