• Publications
  • Influence
Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure
BACKGROUND Increased intracranial pressure as a complication of acute liver failure has a mortality of about 90% in patients who do not respond to treatment with mannitol and ultrafiltration. WeExpand
  • 335
  • 12
Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension.
BACKGROUND AND AIMS About 20% of patients with acute liver failure (ALF) die from increased intracranial pressure (ICP) while awaiting transplantation. This study evaluates the clinical effects andExpand
  • 237
  • 12
Restoration of cerebral blood flow autoregulation and reactivity to carbon dioxide in acute liver failure by moderate hypothermia
In patients with acute liver failure (ALF) and uncontrolled intracranial hypertension, moderate hypothermia (32°C) reduces intracranial pressure (ICP) and cerebral blood flow (CBF), and can be usedExpand
  • 111
  • 8
  • PDF
Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow.
BACKGROUND/AIMS The study aims were to determine the role of inflammation in the pathogenesis of increased intracranial pressure (ICP) in patients with acute liver failure (ALF) and its interplayExpand
  • 177
  • 7
Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe encephalopathy
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whomExpand
  • 97
  • 7
  • PDF
The utilization of liver transplantation in the management of acute liver failure: Comparison between acetaminophen and non‐acetaminophen etiologies
Liver transplantation (LT) may be life‐saving in severe acute liver failure (ALF). The aim of this study was to compare the utilization of LT in acetaminophen and non‐acetaminophen ALF. Between 1992Expand
  • 92
  • 6
Moderate hypothermia prevents cerebral hyperemia and increase in intracranial pressure in patients undergoing liver transplantation for acute liver failure
Background. During orthotopic liver transplantation (OLT) for acute liver failure (ALF), some patients develop acute increases in intracranial pressure (ICP). The authors tested the hypothesis thatExpand
  • 146
  • 5
Invasive pneumococcal disease following adult allogeneic hematopoietic stem cell transplantation
Allogeneic hematopoietic stem cell transplantation (alloHSCT) recipients are at high risk of invasive pneumococcal disease (IPD). We investigated the incidence and risk factors of IPD in alloHSCTExpand
  • 29
  • 3
Disposition Kinetics of Ropivacaine in Humans
The pharmacokinetic characteristics of a new local anesthetic drug, ropivacaine, were determined after intravenous infusion of 50 mg of the hydrochloride salt into six healthy male volunteers.Expand
  • 147
  • 2