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Droplet microfluidics.
Droplet-based microfluidic systems have been shown to be compatible with many chemical and biological reagents and capable of performing a variety of "digital fluidic" operations that can be renderedExpand
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Human neural stem cell growth and differentiation in a gradient-generating microfluidic device.
This paper describes a gradient-generating microfluidic platform for optimizing proliferation and differentiation of neural stem cells (NSCs) in culture. Microfluidic technology has great potentialExpand
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Unique Dielectric Properties Distinguish Stem Cells and Their Differentiated Progeny
The relatively new field of stem cell biology is hampered by a lack of sufficient means to accurately determine the phenotype of cells. Cell‐type‐specific markers, such as cell surface proteins usedExpand
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Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis.
A multifunctional and high-efficiency microfluidic device for droplet generation and fusion is presented. Through unique design of the micro-channels, the device is able to alternately generateExpand
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On-chip generation of microbubbles as a practical technology for manufacturing contrast agents for ultrasonic imaging.
This paper presents a new manufacturing method to generate monodisperse microbubble contrast agents with polydispersity index (sigma) values of <2% through microfluidic flow-focusing. Micron-sizedExpand
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Design of microfluidic channel geometries for the control of droplet volume, chemical concentration, and sorting.
Passive microfluidic channel geometries for control of droplet fission, fusion and sorting are designed, fabricated, and tested. In droplet fission, the inlet width of the bifurcating junction isExpand
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In vitro perfused human capillary networks.
Replicating in vitro the complex in vivo tissue microenvironment has the potential to transform our approach to medicine and also our understanding of biology. In order to accurately model the 3DExpand
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1-Million droplet array with wide-field fluorescence imaging for digital PCR.
Digital droplet reactors are useful as chemical and biological containers to discretize reagents into picolitre or nanolitre volumes for analysis of single cells, organisms, or molecules. However,Expand
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PLGA micro/nanosphere synthesis by droplet microfluidic solvent evaporation and extraction approaches.
In this paper, we present two approaches for the synthesis of poly(lactide-co-glycolide) (PLGA) micro/nanospheres using non-toxic organic solvents in droplet-based microfluidic platforms. SolventExpand
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Engineering microscale cellular niches for three-dimensional multicellular co-cultures.
Modeling the in vivo microenvironment typically involves placing cells in a three-dimensional (3D) extracellular matrix (ECM) in physiologically relevant context with respect to other cells. TheExpand
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