• Publications
  • Influence
Caffeic acid esters and lignans from Piper sanguineispicum.
TLDR
Three new caffeic acid esters, four new lignans, and the known compounds (7'S)-parabenzlactone, dihydrocubebin, and justiflorinol have been isolated from leaves of Piper sanguineispicum by spectroscopic methods and chemical methods.
Synthesis and cytotoxic activities of usnic acid derivatives.
TLDR
The more active derivative (1,8-diaminooctane derivative) displayed similar activities on all cancer cell lines studied and induced apoptosis and alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, had no effect on the activity of the polyamine derivatives.
Dihydrochalcones and benzoic acid derivatives from Piper dennisii.
TLDR
Among them, compound 10 exhibited the best antileishmanial activity against axenic amastigote forms of Leishmania amazonensis, with low cytotoxicity on murine macrophages.
Leishmanicidal compounds and potent PPARγ activators from Renealmia thyrsoidea (Ruiz & Pav.) Poepp. & Endl.
TLDR
Phytochemical investigation of Renealmia thyrsoidea has led to the isolation of leishmanicidal compounds from the leaves and potent PPARγ activators from the rhizomes, thus revealing interesting immunomodulatory properties.
Matrix-Free UV-Laser Desorption Ionization Mass Spectrometry as a Versatile Approach for Accelerating Dereplication Studies on Lichens.
TLDR
It was shown that LDI ionization leads to strong molecular ion formation with little fragmentation, thus, facilitating straightforward spectra interpretation and representing a valuable alternative to time-consuming LC-MS analysis.
In situ DART-MS as a Versatile and Rapid Dereplication Tool in Lichenology: Chemical Fingerprinting of Ophioparma ventosa.
TLDR
In situ DART-MS analyses of Ophioparma ventosa provided an extensive chemical profile and noteworthy pinpointed miriquidic acid, an unusual lichen depside so far unknown within this species, granting a first insight into the distribution of the metabolites within the lichen.
Depsides: Lichen Metabolites Active against Hepatitis C Virus
TLDR
Interestingly, atranorin (1), bearing an aldehyde function at C-3, inhibited only viral entry, whereas the synthetic compounds 5 and 6, bearing a hydroxymethyl and a methyl function, respectively, atC-3 interfered with viral replication.
Spatial mapping of lichen specialized metabolites using LDI-MSI: chemical ecology issues for Ophioparma ventosa
TLDR
The analytical strategy presented herein offers new perspectives to access the sharp distribution of lichen metabolites from regular razor blade-sectioned slices.
Which Specialized Metabolites Does the Native Subantarctic Gastropod Notodiscus hookeri Extract from the Consumption of the Lichens Usnea taylorii and Pseudocyphellaria crocata?
TLDR
Notodiscus hookeri appears as a generalist lichen feeder able to consume toxic metabolite-containing lichens, independently of the ecophenotype, and might be based on four non-exclusive processes according to the concerned metabolites.
Minor Pyranonaphthoquinones from the Apothecia of the Lichen Ophioparma ventosa.
Four new quinonoid naphthopyranones, ophioparmin (1), 4-methoxyhaemoventosins (2a and 2b), and 4-hydroxyhaemoventosin (3), together with anhydrofusarubin lactone (4) and haemoventosin (5) were
...
1
2
3
...