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- Publications
- Influence
Causes and outcomes of markedly elevated C-reactive protein levels.
- A. Landry, P. Docherty, S. Ouellette, L. Cartier
- Medicine
- Canadian family physician Medecin de famille…
- 1 June 2017
OBJECTIVE
To characterize the causes of marked elevation of C-reactive protein (CRP) levels, investigate patient outcomes, and examine factors that might influence the CRP response.
DESIGN
Health… Expand
Multimorbidity states associated with higher mortality rates in organ dysfunction and sepsis: a data-driven analysis in critical care
- Z. Zador, A. Landry, M. Cusimano, N. Geifman
- Medicine
- Critical Care
- 8 July 2019
BackgroundSepsis remains a complex medical problem and a major challenge in healthcare. Diagnostics and outcome predictions are focused on physiological parameters with less consideration given to… Expand
Using artificial neural networks to identify patients with concussion and postconcussion syndrome based on antisaccades.
- A. Landry, W. Ting, Z. Zador, Alireza Sadeghian, M. Cusimano
- Medicine
- Journal of neurosurgery
- 1 October 2019
OBJECTIVEArtificial neural networks (ANNs) have shown considerable promise as decision support tools in medicine, including neurosurgery. However, their use in concussion and postconcussion syndrome… Expand
Landscape of immune cell gene expression is unique in predominantly WHO grade 1 skull base meningiomas when compared to convexity
- Z. Zador, A. Landry, M. Balas, M. Cusimano
- Biology, Medicine
- Scientific Reports
- 3 June 2020
Modulation of tumor microenvironment is an emerging frontier for new therapeutics. However in meningiomas, the most frequent adult brain tumor, the correlation of microenvironment with tumor… Expand
“Skull base meningiomas have a distinct immune landscape.”
- Z. Zador, A. Landry, M. Balas, M. Cusimano
- Biology
- 20 January 2019
Modulation of tumor microenvironment is an emerging frontier for new therapeutics. However in meningiomas, the most frequent adult brain tumor, the correlation of microenvironment with tumor… Expand
Data Driven Analysis Reveals Shared Transcriptome Response, Immune Cell Composition, and Distinct Mortality Rates Across Differing Etiologies of Critical Illness
- Z. Zador, A. Landry, M. Balas, J. Marshall, M. Cusimano
- Medicine
- Critical care medicine
- 1 March 2020
Supplemental Digital Content is available in the text. Objectives: Sepsis and trauma are common health problems and provide great challenges in critical care. Diverse patient responses to these… Expand
Distinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma
- A. Landry, M. Balas, S. Alli, J. Spears, Z. Zador
- Biology, Medicine
- Scientific reports
- 11 November 2020
Tumor-associated macrophages (TAMs) constitute up to 50% of tumor bulk in glioblastoma (GBM) and play an important role in tumor maintenance and progression. The recently discovered differences… Expand
Reclassification of breast cancer: Towards improved diagnosis and outcome
- A. Landry, Z. Zador, R. Haq, M. Cusimano
- Medicine
- PloS one
- 22 May 2019
Background The subtyping of breast cancer based on features of tumour biology such as hormonal receptor and HER2 status has led to increasingly patient-specific treatment and thus improved outcomes.… Expand
“Homogenous subgroups of atypical meningiomas defined using oncogenic signatures: basis for a new grading system?”
- Z. Zador, A. Landry, Ashirbani Saha, M. Cusimano
- Medicine, Biology
- 14 December 2018
Meningiomas are the most common brain tumor with a prevalence of 3% in the population. Histological grading of meningiomas (1 through 3) has a major role in determining treatment choice and… Expand
Meta-gene markers predict meningioma recurrence with high accuracy
- Z. Zador, A. Landry, B. Haibe-Kains, M. Cusimano
- Medicine, Biology
- 4 July 2019
Background Meningiomas, the most common adult brain tumors, recur in up to half of cases[1–3]. This requires timely intervention and therefore accurate risk assessment of recurrence is essential. Our… Expand
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