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Phenotypical properties associated with virulence from clinical isolates belonging to the Candida parapsilosis complex.
- É. A. Abi-chacra, Lucieri O.P. Souza, +10 authors A. L. Santos
- Biology, Medicine
- FEMS yeast research
- 1 December 2013
The production of virulence attributes in three reference strains and 11 clinical isolates primarily identified as Candida parapsilosis was evaluated. Morphological and phenotypical tests were not… Expand
Detection of sialoglycomolecules in five plant trypanosomatids and in an insect phytophagous isolate
The sialoglycoprotein profiles of five plant trypanosomatids (Phytomonas spp.) and of one flagellate (Herpetomonas sp.) isolated from the salivary gland of a phytophagous insect (Phthia picta) were… Expand
Chondrogenesis of the limbs and mesopodial ossification of Podocnemis expansa Schweigger, 1812 (Testudines: Podocnemidae)
- L. G. Vieira, A. L. Santos, F. C. Lima, L. R. Moura
- Biology, Medicine
- Journal of morphology
- 1 April 2011
We address the chondrogenic formation of the limbs and the mesopodial ossification pattern of the Pleurodira Podocnemis expansa, to resolve the homology of these elements as well as the pattern of… Expand
In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes
1,10-Phenanthroline (phen, 5), 1,10-phenanthroline-5,6-dione (phendione, 6), [Cu(phendione)3](ClO4)2·4H2O (12) and [Ag(phendione)2]ClO4 (13) are highly active, in vitro, against a range of normal and… Expand
Protease expression by microorganisms and its relevance to crucial physiological/pathological events.
- A. L. Santos
- 26 March 2011
The treatment of infections caused by fungi and trypanosomatids is difficult due to the eukaryotic nature of these microbial cells, which are similar in several biochemical and genetic aspects to… Expand
Calpains: potential targets for alternative chemotherapeutic intervention against human pathogenic trypanosomatids.
The treatment for both leishmaniasis and trypanosomiasis, which are severe human infections caused by trypanosomatids belonging to Leishmania and Trypanosoma genera, respectively, is extremely… Expand
Aspartic protease inhibitors: effective drugs against the human fungal pathogen Candida albicans.
Candida albicans can invade humans and may lead to mucosal and skin infections or to deep-seated mycoses of almost all inner organs, especially in immunocompromised patients. In this context, both… Expand
Insights into the social life and obscure side of Scedosporium/Lomentospora species: ubiquitous, emerging and multidrug-resistant opportunistic pathogens
- Thaís P. Mello, V. Bittencourt, L. Liporagi-Lopes, A. C. Aor, M. Branquinha, A. L. Santos
Abstract The undeniable relevance of fungal infections caused by both yeasts and molds has considerably augmented over the last four decades, becoming a serious health public problem in hospitals… Expand
Aspartic Peptidase Inhibitors as Potential Bioactive Pharmacological Compounds Against Human Fungal Pathogens
- A. L. Santos
The development of novel antifungal drugs is becoming more demanding every day since existing drugs either have too many side-effects or they tend to lose effectiveness due to resistant fungal… Expand
Biological Roles of Peptidases in Trypanosomatids
- Alane Beatriz Vermelho, M. Branquinha, C. M. d'Avila-Levy, A. L. Santos, Edilma Paraguai de Souza Dias, A. C. Melo
- 18 March 2010
In this review, we report the recent developments in the characterization of peptidases and their possible biological functions in the Trypanosomatidae family. The focus will be on peptidases from… Expand