International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels
- W. Catterall, A. L. Goldin, S. Waxman
- BiologyPharmacological Reviews
- 1 December 2005
The molecular relationships and physiological roles of these sodium channel proteins are presented and comprehensive information on their molecular, genetic, physiological, and pharmacological properties is provided.
Resurgence of sodium channel research.
- A. L. Goldin
- BiologyAnnual Review of Physiology
- 2001
A variety of isoforms of mammalian voltage-gated sodium channels have been described, and the alpha subunit isoforms have distinct patterns of development and localization in the nervous system, skeletal and cardiac muscle.
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.
- J. West, D. Patton, T. Scheuer, Y. Wang, A. L. Goldin, W. Catterall
- BiologyProceedings of the National Academy of Sciences…
- 15 November 1992
It is proposed that the hydrophobic cluster of Ile-1488, Phe-1489, and Met-1490 serves as a hydrophilic latch that stabilizes the inactivated state in a hinged-lid mechanism of Na(+)-channel inactivation.
Nomenclature of Voltage-Gated Sodium Channels
- A. L. Goldin, R. Barchi, W. Catterall
- BiologyNeuron
- 1 March 2000
Maintenance of Xenopus laevis and oocyte injection.
- A. L. Goldin
- BiologyMethods in Enzymology
- 1992
Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel.
- L. Isom, K. De Jongh, W. Catterall
- BiologyScience
- 8 May 1992
Results indicate that the beta 1 subunit is crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the rat brain sodium channel.
Mechanisms of sodium channel inactivation
- A. L. Goldin
- BiologyCurrent Opinion in Neurobiology
- 1 June 2003
Functional Analysis of the Mouse Scn8a Sodium Channel
- Marianne R. Smith, Raymond D. Smith, N. W. Plummer, M. Meisler, A. L. Goldin
- BiologyJournal of Neuroscience
- 15 August 1998
The unique persistent current observed for Scn8a channels is consistent with the hypothesis that this channel is responsible for distinct sodium conductances underlying repetitive firing of action potentials in Purkinje neurons.
Evolution of voltage-gated Na(+) channels.
- A. L. Goldin
- BiologyJournal of Experimental Biology
- 1 March 2002
Vertebrate and invertebrate Na(+) channels appear to be derived from a single primordial channel that subsequently evolved independently in the two lineages.
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