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Ocular inserts — Advancement in therapy of eye diseases
TLDR
The release of drug from the insert depends upon the diffusion, osmosis, and bioerosion of the drug, and this article is an attempt to present a brief about this newer drug delivery system.
Inducible Clindamycin Resistance among Clinical Isolates of Staphylococcus aureus from Sub Himalayan Region of India.
TLDR
Routine testing of inducible clindamycin resistance at individual settings is recommended to guide optimum therapy and to avoid treatment failure in patients with S. aureus from this region of the country.
Social isolation mediated anxiety like behavior is associated with enhanced expression and regulation of BDNF in the female mouse brain
TLDR
This study suggests that social isolation mediated anxiety like behavior is associated with up-regulation of BDNF expression and concomitant increase in the expression of CBP, CREB-1, Limk-1 and miRNA-132, and decrease in theexpression of HDAC-2 and mi RNA-134 in the cerebral cortex.
Role of 18F-FDG PET/CT in Detecting Recurrent Gallbladder Carcinoma
TLDR
Routine use of PET/CT in patients with gallbladder cancer with suspicion of recurrent disease can detect recurrence early and change the subsequent management, and integrated FDG PET/ CT showed a better specificity than CI for detection of recurrence.
Unanticipated cardiac arrest under spinal anesthesia: An unavoidable mystery with review of current literature
TLDR
The present case reports are an important addition to a series of recently published mishaps that occurred during spinal anesthesia in young and healthy patients.
Comparison of conventional Pap smear and liquid-based cytology: A study of cervical cancer screening at a tertiary care center in Bihar.
TLDR
LBC has been found to be more superior to conventional smears only with respect to lesser number of unsatisfactory smears, but considering the economic implications of LBC, conventional Pap is more feasible in this setting.
To Identify Myocardial Changes in Severely Malnourished Children: A Prospective Observational Study
TLDR
Electrocardiographic changes may be of help in assessing the severity and prognosis of severe acute malnutrition and the reversibility of ECG changes with dietary treatment suggests that the cardiac changes are not permanent in nature and may not affect adult life if the malnutrition is corrected.
Age-Dependent Decline of Nogo-A Protein in the Mouse Cerebrum
TLDR
It is speculated that the downregulation of Nogo-A protein might have a role in the altered synaptic plasticity during aging.
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