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Current and novel therapeutic molecules and targets in Alzheimer's disease.
Alzheimer's disease (AD) is a neurodegenerative disorder in which the death of brain cells causes memory loss and cognitive decline, i.e., dementia. The disease starts with mild symptoms and… Expand
Strategies for the Production of Recombinant Protein in Escherichia coli
In the recent past years, a large number of proteins have been expressed in Escherichia coli with high productivity due to rapid development of genetic engineering technologies. There are many hosts… Expand
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects
- J. Hoskins, Leslie O. Ofori, +11 authors C. Thornton
- Biology, Medicine
- Nucleic acids research
- 5 May 2014
Myotonic dystrophy type 1 (DM1) is a dominantly inherited neuromuscular disorder resulting from expression of RNA containing an expanded CUG repeat (CUGexp). The pathogenic RNA is retained in nuclear… Expand
Overview of the stability of α-chymotrypsin in different solvent media.
Chitosan/TiO2 composite membrane improves proliferation and survival of L929 fibroblast cells: Application in wound dressing and skin regeneration.
- S. S. Behera, Urmimala Das, A. Kumar, A. Bissoyi, A. Singh
- Chemistry, Medicine
- International journal of biological…
- 1 May 2017
The microbial infection and growth of fibroblasts are the critical factors for the effective wound healing. The natural polymer-based dressing membranes may mimic extracellular matrix to support the… Expand
Amplified fragment length polymorphism (AFLP) analysis is useful for distinguishing Leishmania species of visceral and cutaneous forms.
- A. Kumar, V. R. Boggula, P. Misra, S. Sundar, A. K. Shasany, A. Dube
- Medicine, Biology
- Acta tropica
- 1 February 2010
The Leishmania strains belonging to cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) have been reported to possess close homology in genome profiles. To confirm this on genetic basis an… Expand
Evolution of Marine Organisms under Climate Change at Different Levels of Biological Organisation
Research to date has suggested that both individual marine species and ecological processes are expected to exhibit diverse responses to the environmental effects of climate change. Evolutionary… Expand
An improved method for high-level soluble expression and purification of recombinant amyloid-beta peptide for in vitro studies.
- Gaurav Chhetri, Tripti Pandey, Ramesh Chinta, A. Kumar, Timir Tripathi
- Medicine, Chemistry
- Protein expression and purification
- 1 October 2015
Amyloid-beta (Aβ) peptide mediates several neurodegenerative diseases. The 42 amino acid (Aβ1-42) is the predominant form of peptide found in the neuritic plaques and has been demonstrated to be… Expand
Evaluations of soil Fertility Status of Available Major Nutrients ( N,P & K) and Micro Nutrients (Fe, Mn, Cu & Zn) in Vertisol of Kabeerdham District of Chhat tisgarh, India
Grid based (GPS) surface (0-15 cm) soil samples by systemati c survey were collected from 4 blocks, 84 selected villages in Kabeerdham district were 297samples identified fro m Vertisol. These soil… Expand