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- Publications
- Influence
Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.
- G. Chlipala, M. Sturdy, +5 authors J. Orjala
- Chemistry, Medicine
- Journal of natural products
- 24 September 2010
Material collected from a parkway in the city of Chicago afforded the isolation of a Nostoc species (UIC 10022A). The extract of this strain displayed significant inhibition of the 20S proteasome as… Expand
Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators.
- A. D. Jain, Haranatha R. Potteti, +8 authors T. Moore
- Chemistry, Medicine
- European journal of medicinal chemistry
- 20 October 2015
Activation of the transcription factor Nrf2 has been posited to be a promising therapeutic strategy in a number of inflammatory and oxidative stress diseases due to its regulation of detoxifying… Expand
An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp.
- Shunyan Mo, A. Krunic, S. D. Pegan, S. Franzblau, J. Orjala
- Biology, Medicine
- Journal of natural products
- 4 November 2009
Scytoscalarol (1), a antimicrobial sesterterpene bearing a guanidino group, was isolated from the cultured cyanobacterium Scytonema sp. (UTEX 1163) by bioassay-guided fractionation. The chemical… Expand
Merocyclophanes A and B, antiproliferative cyclophanes from the cultured terrestrial Cyanobacterium Nostoc sp.
- Hahk-Soo Kang, B. Santarsiero, +6 authors J. Orjala
- Biology, Medicine
- Phytochemistry
- 1 July 2012
The cell extract of a cultured terrestrial Nostoc sp. (UIC 10062), obtained from a sample collected at Grand Mere State Park in Michigan, displayed antiproliferative activity against the HT-29 human… Expand
Carbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp.
- S. Luo, Hahk-Soo Kang, +6 authors J. Orjala
- Chemistry, Medicine
- Tetrahedron letters
- 15 January 2014
Two new (1 and 2) and three known (3-5) carbamidocyclophanes were isolated from a cultured freshwater cyanobacterium Nostoc sp. (UIC 10274) obtained from a sample collected at Des Plaines, Illinois.… Expand
Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua.
- Shunyan Mo, A. Krunic, G. Chlipala, J. Orjala
- Chemistry, Medicine
- Journal of natural products
- 16 April 2009
Five new antibacterial ambiguine K-O isonitriles (1-5) and eight previously described indole alkaloids were isolated from the cultured cyanobacterium Fischerella ambigua (UTEX 1903) by… Expand
Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua.
- Shunyan Mo, A. Krunic, B. Santarsiero, S. Franzblau, J. Orjala
- Biology, Medicine
- Phytochemistry
- 1 December 2010
Four hapalindole-related alkaloids, namely fischambiguines A and B, ambiguine P, ambiguine Q nitrile as well as ambiguine G nitrile were identified from the cultured cyanobacterium Fischerella… Expand
Nitrile-Containing Fischerindoles from the Cultured Cyanobacterium Fischerella sp.
Chemical investigation of the cultured cyanobacterium Fischerella sp. (SAG strain number 46.79) led to the isolation of four nitrile-containing indole alkaloids, namely 12-epi-fischerindole I nitrile… Expand
Minutissamides A-D, antiproliferative cyclic decapeptides from the cultured cyanobacterium Anabaena minutissima.
- Hahk-Soo Kang, A. Krunic, Q. Shen, S. Swanson, J. Orjala
- Biology, Medicine
- Journal of natural products
- 22 July 2011
Four cyclic decapeptides, minutissamides A-D (1-4), were isolated from the cultured cyanobacterium Anabaena minutissima (UTEX 1613). The planar structures were determined using various spectroscopic… Expand
Stigonemapeptin, an Ahp-containing depsipeptide with elastase inhibitory activity from the bloom-forming freshwater cyanobacterium Stigonema sp.
- Hahk-Soo Kang, A. Krunic, J. Orjala
- Chemistry, Medicine
- Journal of natural products
- 6 April 2012
Stigonemapeptin (1), a depsipeptide containing an Ahp (3-amino-6-hydroxy-2-piperidone) residue, was isolated from a bloom sample of the freshwater cyanobacterium Stigonema sp. collected from North… Expand