Skip to search formSkip to main contentSkip to account menu
Chemotherapy‐induced peripheral neurotoxicity: A critical analysis
TLDR
This review will address the increasing importance and challenge of chemotherapy‐induced neurotoxicity, with a focus on neuropathy associated with the treatment of breast cancer, colorectal cancer, testicular cancer, and hematological cancers.
View on Wiley
Riluzole, neuroprotection and amyotrophic lateral sclerosis.
TLDR
The present review summarises the known chemical and pharmacological properties of riluzole, and the hypothesis that Na+ conductances may be involved in the processes of neuronal and axonal degeneration in ALS will be explored.
View on PubMed
Neurological complications of chronic kidney disease
TLDR
For patients with autonomic neuropathy, specific treatments, including sildenafil for impotence and midodrine for intradialytic hypotension, are effective and well tolerated, and exercise training programs and carnitine supplementation might be beneficial for neuromuscular complications.
View on Nature
Mechanisms underlying chemotherapy-induced neurotoxicity and the potential for neuroprotective strategies.
TLDR
Improved understanding of the pathophysiology of chemotherapy-induced neurotoxicity will inevitably assist in the development of future neuroprotective strategies and in the design of novel chemotherapies with improved toxicity profiles.
View on PubMed
Axonal ion channels from bench to bedside: A translational neuroscience perspective
View on Elsevier
Long-term neuropathy after oxaliplatin treatment: challenging the dictum of reversibility.
TLDR
These findings establish the persistence of subjective and objective deficits in oxaliplatin-treated patients post-oxali Platin, suggesting that sensory neuropathy is a long-term outcome, thereby challenging the literature on the reversibility of oxali platin-induced neuropathy.
View on PubMed
Bell's palsy: aetiology, clinical features and multidisciplinary care
TLDR
A patient centred approach utilising physiotherapy, targeted botulinum toxin injection and selective surgical intervention has reduced the burden of long-term disability in facial palsy.
View on BMJ
Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy.
TLDR
Sensory axonal excitability techniques may provide a means to identify pre-clinical oxaliplatin-induced nerve dysfunction prior to the onset of chronic neuropathy, and patients with severe neurotoxicity at treatment completion demonstrated greater excitability changes than those left with mild or moderate neurotoxicity.
View on PubMed
Acute abnormalities of sensory nerve function associated with oxaliplatin-induced neurotoxicity.
TLDR
Sensory axonal excitability techniques may facilitate identification of Na+ channel dysfunction in oxaliplatin-induced neurotoxicity and thereby provide a method to identify patients at risk for neurotoxicity to target those most likely to benefit from future neuroprotective strategies.
View on PubMed
The effects of alterations in conditioning stimulus intensity on short interval intracortical inhibition
View on Elsevier
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License