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Drug-eluting bioabsorbable stents - an in vitro study.
- J. Mikkonen, I. Uurto, +6 authors M. Kellomäki
- Materials Science, Medicine
- Acta biomaterialia
- 1 October 2009
The aim of this study was to investigate the drug elution properties of novel drug-eluting bioabsorbable stents in vitro with four different drugs: dexamethasone, indomethacin, simvastatin and… Expand
Urethral in situ biocompatibility of new drug‐eluting biodegradable stents: an experimental study in the rabbit
To assess the effect of drug‐eluting properties on the degradation process and the biocompatibility of biodegradable drug‐eluting urethral stents.
Biodegradable braided poly(lactic‐co‐glycolic acid) urethral stent combined with dutasteride in the treatment of acute urinary retention due to benign prostatic enlargement: a pilot study
To evaluate, in a pilot study, the efficacy and safety of combining a braided poly(lactic‐co‐glycolic acid) (PLGA, a copolymer of l‐lactide and glycolide) urethral stent and dutasteride in the… Expand
Tissue biocompatibility of new biodegradable drug-eluting stent materials
- I. Uurto, A. Kotsar, +7 authors Juha-Pekka Salenius
- Materials Science, Medicine
- Journal of materials science. Materials in…
- 17 April 2007
Drug-eluting stents are a recent innovation for endovascular and endourethral purposes. The aim of this study was to assess the biocompatibility of new biodegradable drug-eluting stent materials in… Expand
Biocompatibility of new drug-eluting biodegradable urethral stent materials.
OBJECTIVES To investigate the effects of biodegradable stent material (poly-96L/4D-lactic acid [PLA]) on the production of cytokines and other inflammatory mediators in vitro and the biocompatibility… Expand
Preclinical evaluation of new indomethacin-eluting biodegradable urethral stent.
PURPOSE To evaluate the effect of an indomethacin-eluting biodegradable urethral stent on the production of inflammatory cytokines in vitro and the degradation and biocompatibility of the new stent… Expand
A new biodegradable braided self-expandable PLGA prostatic stent: an experimental study in the rabbit.
PURPOSE The biodegradable PLGA (a copolymer of L-lactide and glycolide) urethral stent with a spiral configuration has been used clinically for the prevention of postoperative urinary retention after… Expand
Dexamethasone-eluting vascular stents.
- M. Hämäläinen, R. Nieminen, +8 authors E. Moilanen
- Basic & clinical pharmacology & toxicology
- 1 May 2013
Percutaneous transluminal angioplasty (PTA) with stenting is widely used in the treatment of vascular disorders, but restenosis remains a significant problem. Drug-eluting stents (DES) have been… Expand
The effect of pH on the degradation of biodegradable poly(L-lactide-co-glycolide) 80/20 urethral stent material in vitro.
PURPOSE To investigate in vitro whether pH ranging between 6 and 9 has an effect on the degradation of stent fibers made of poly(l-lactide-co-glycolide) (PLGA) 80/20. MATERIALS AND METHODS The… Expand
Muraglitazar-eluting bioabsorbable vascular stent inhibits neointimal hyperplasia in porcine iliac arteries.
- I. Uurto, M. Hämäläinen, +6 authors Juha-Pekka Salenius
- Journal of vascular and interventional radiology…
PURPOSE To evaluate the biocompatibility of a new muraglitazar-eluting polylactide copolymer stent and investigate its ability to prevent the formation of intimal hyperplasia. MATERIALS AND METHODS… Expand