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Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones.
TLDR
Both isomers of ferrocene carboxaldehyde displayed in vitro toxicity against B16 melanoma and Vero cell lines in the micromolar range and inhibited the kinase VEGFR-2 with IC(50) values of ca.
Novel Biocompatible Cationic Copolymers Based on Polyaspartylhydrazide Being Potent as Gene Vector on Tumor Cells
TLDR
In vivo application studies confirmed the biocompatibility of PAHy–CPTA copolymers and evidenced a faster binding of these polyplexes with cells compared to DNA/LPEI polyplexe.
Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity.
The reaction of the five-membered C,N-palladacycle [(L)PdCl](2), where LH = 1-methyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one, with 1,2-ethanebis(diphenylphosphine), dppe, leads to the formation of
An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin.
TLDR
The catechin, epigallocatechin gallate, found in green tea, has inhibitory activity against a number of protein toxins and was investigated in relation to its impact upon ricin toxin (RT) in vitro, suggesting that eGCG may provide a starting point to refine biocompatible substances that can reduce the lethality of ricin.
Bioactivity, biocompatibility and antimicrobial properties of a chitosan-mineral composite for periodontal tissue regeneration
A composite membrane of the polymer, chitosan, and the silver-exchanged mineral phase, tobermorite, was prepared by solvent casting and characterised by scanning electron microscopy and Fourier
Effect of Calcium Precursor on the Bioactivity and Biocompatibility of Sol-Gel-Derived Glasses
TLDR
Overall, calcium ethoxide was found to be the preferred precursor with respect to extent of calcium-incorporation, homogeneity, bioactivity and biocompatibility of the alkoxide-derived glasses.
Oro-dispersible tablets of ayurvedic powder for improving taste, compliance, ease and accuracy of administration
Most of the ayurvedic medicines are in the form of powder. Being in powder form the administration of accurate dose with ease is a problem. They may have some kind of unacceptable bitter taste.
Nanomedicine based approaches for combating viral infections.
  • Saurabh Shah, M. Chougule, +5 authors Saurabh Srivastava
  • Medicine
    Journal of controlled release : official journal…
  • 7 August 2021
TLDR
Current review emphasizes over an enhanced understanding of how different lipid, polymer and elemental based nanoformulations could be potentially and precisely used to bridle the said drawbacks in antiviral therapy.
Imaging select mammalian organelles using fluorescent microscopy: application to drug delivery.
TLDR
The microscopic imaging of specific organelles has become a staple of the single-cell assay and has helped define the molecular regulation of many physiological processes and an evaluation of the intracellular trafficking of both biological and synthetic macromolecules is allowed.
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