A. Komaroff

Publications471
h-index42
Citations11,197
Highly Influential Citations776
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The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study
We have developed a conceptual framework and a set of research guidelines for use in studies of the chronic fatigue syndrome. The guidelines cover the clinical and laboratory evaluation of persons… Expand
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The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group.
The complexities of the chronic fatigue syndrome and the methodologic problems associated with its study indicate the need for a comprehensive, systematic, and integrated approach to the evaluation,… Expand
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Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
Chronic fatigue syndrome (CFS) is a serious systemic illness of unknown cause. A recent study identified DNA from a xenotropic murine leukemia virus-related virus (XMRV) in peripheral blood… Expand
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The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro
Previous research has suggested that human herpesvirus-6 (HHV-6) may integrate into host cell chromosomes and be vertically transmitted in the germ line, but the evidence—primarily fluorescence in… Expand
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Prevalence of fatigue and chronic fatigue syndrome in a primary care practice.
BACKGROUND Our goals were to determine the prevalence of unusual, debilitating fatigue and the frequency with which it was associated with the chronic fatigue syndrome (CFS) or other physical or… Expand
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Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus.
An independent strain (JI) of human herpesvirus 7 (HHV-7) was isolated from a patient with chronic fatigue syndrome (CFS). No significant association could be established by seroepidemiology between… Expand
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A randomized trial of a computer-based intervention to reduce utilization of redundant laboratory tests.
PURPOSE To determine the impact of giving physicians computerized reminders about apparently redundant clinical laboratory tests. SUBJECTS AND METHODS We performed a prospective randomized… Expand
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Does the chronic fatigue syndrome involve the autonomic nervous system?
PURPOSE To investigate the role of the autonomic nervous system in the symptoms of patients with chronic fatigue syndrome (CFS) and delineate the pathogenesis of the orthostatic Intolerance and… Expand
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Review, part 1: Human herpesvirus‐6‐basic biology, diagnostic testing, and antiviral efficacy
Louis Flamand, Anthony L. Komaroff, Jesse H. Arbuckle, Peter G. Medveczky, and Dharam V. Ablashi* Department of Microbiology, Infectious Diseases and Immunology, Faculty of Medicine, Laval… Expand
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Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction.
A sensitive and specific polymerase chain reaction method for the detection of human herpesvirus 6 (HHV-6) DNA in serum or plasma has been developed. In total, 157 human serum or plasma samples were… Expand
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