A. Koga

Publications91
h-index20
Citations1,520
Highly Influential Citations50
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Transposable element in fish
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Excision of the tol2 transposable element of the medaka fish, Oryzias latipes, in zebrafish, Danio rerio.
The Tol2 element is a transposable element in Oryzias latipes (the medaka fish) found in the tyrosinase gene locus of the tyrosinase-deficient mutant medaka fish and has been shown to be excised from… Expand
  • 175
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Establishment of Gal4 transgenic zebrafish lines for analysis of development of cerebellar neural circuitry.
The cerebellum is involved in some forms of motor coordination and motor learning. Here we isolated transgenic (Tg) zebrafish lines that express a modified version of Gal4-VP16 (GFF) in the… Expand
  • 39
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Germline transgenesis of zebrafish using the medaka Tol1 transposon system
Tol1 is a DNA‐based transposable element first identified from an albino mutant medaka fish. It has been demonstrated to function as an efficient gene transfer vector in mammalian cells. We now… Expand
  • 41
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Evolution of subterminal satellite (StSat) repeats in hominids
Subterminal satellite (StSat) repeats, consisting of 32-bp-long AT-rich units (GATATTTCCATGTT(T/C)ATACAGATAGCGGTGTA), were first found in chimpanzee and gorilla (African great apes) as one of the… Expand
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Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes
In the medaka fish (Oryzias latipes) many mutants for body color have been isolated. A typical example is the recessive oculocutaneous albino mutant i, which has amelanotic skin and red-colored eyes… Expand
  • 79
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Evidence for recent invasion of the medaka fish genome by the Tol2 transposable element.
Tol2 is a transposable element of the terminal-inverted-repeat class, residing in the genome of the medaka fish Oryzias latipes. The genus Oryzias contains more than 10 species for which phylogenetic… Expand
  • 54
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Amino acid sequence of a putative transposase protein of the medaka fish transposable element Tol2 deduced from mRNA nucleotide sequences
Tol2 is a terminal‐inverted repeat transposable element of the medaka fish Oryzias latipes. It is one of a few elements of this class so far demonstrated to be active in vertebrates, thus providing a… Expand
  • 26
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The tyrosinase gene from medakafish: transgenic expression rescues albino mutation.
We have determined the 9.8 kb genomic nucleotide sequence of the tyrosinase gene and its 5 upstream region from a teleost, medakafish (Oryzias latipes), and shown that the coding region is composed… Expand
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The medaka fish Tol2 transposable element can undergo excision in human and mouse cells
AbstractTol2 is an active DNA-based transposable element identified in the medaka fish, Oryzias latipes. Originating from a vertebrate and belonging to the hAT (hobo/ Activator/ Tam3) transposable… Expand
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