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NMDAR dependent intracellular responses associated with cocaine conditioned place preference behavior
HighlightsCocaine‐CPP is blocked by NMDAR antagonism during conditioning.NMDAR antagonism reduces NAc pERK and pCREB and CPu &Dgr;FosB and SIRT2 levels.NAc pERK levels during cocaine‐CPP expressionExpand
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Sexually dimorphic intracellular responses after cocaine-induced conditioned place preference expression
Sex differences in cocaine's mechanisms of action and behavioral effects have been widely reported. However, little is known about how sex influences intracellular signaling cascades involved withExpand
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Region and context-specific intracellular responses associated with cocaine-induced conditioned place preference expression
The development and maintenance of cocaine addiction depend heavily on learned reward-environment associations that can induce drug-seeking behavior and relapse. Understanding the mechanismsExpand
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Region specific sexually dimorphic intracellular responses after cocaine-induced conditioned place preference expression
Results: Among 12,349 HIV-positive individuals observed in BC between 1996 and 2010, 1811 (14.7%) accessed OST, and 1337 (10.8%) were eligible for our study. Subjects were 39% female, were of medianExpand
Sex differences in memory and intracellular signaling after methamphetamine binge treatment
Methamphetamine is a neurotoxic psychostimulant known to cause cell death and terminal degradation of dopaminergic neurons in the striatum concomitant with memory deficits. However, most of theExpand
Sex difference in behavioral effects of the THC agonist CP55,940
Aims: Attentional biases (AB) interfere with decision making processes and AB to drug cues is a cardinal feature of addiction that may contribute to relapse. Thus it is critical to identify theExpand