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Extracts from Epilobium sp. herbs induce apoptosis in human hormone‐dependent prostate cancer cells by activating the mitochondrial pathway
The aim of this work was to determine the effect of standardized aqueous extracts from Epilobium angustifolium L., E. parviflorum Schreb. and E. hirsutum L. herbs on the apoptosis of
Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibit LPS-induced inflammation in RAW 264.7 murine macrophages.
TLDR
The anti-inflammatory effects of urolithins at concentrations that are physiologically relevant for gut tissues (≥40 μM), as revealed in this study, support the data from in vivo studies showing the beneficial effects of ellagitannin-rich products toward intestinal inflammation.
Chemical composition, antioxidative and anti-inflammatory activity of extracts prepared from aerial parts of Oenothera biennis L. and Oenothera paradoxa Hudziok obtained after seeds cultivation.
TLDR
Both O. paradoxa extract and O. biennis extract exhibited anti-inflammatory activity by the inhibition of hyaluronidase and lipoxygenase in a concentration-dependent manner and may be explained by its higher oenothein B content.
Screening of traditional European herbal medicines for acetylcholinesterase and butyrylcholinesterase inhibitory activity
TLDR
The results show that further investigations of the extracts of arnica, rue and St. John's Wort are needed to identity the compounds responsible for the AChE and BuChE inhibitory activity.
Novel biological properties of Oenothera paradoxa defatted seed extracts: effects on metallopeptidase activity.
TLDR
In this study, for the first time, the in vitro metallopeptidase model is used for the identification of a potential novel activity of defatted evening primrose seed extracts and four active compounds are identified: (-)-epicatechin gallate, proanthocyanidin B3, oenothein B, and penta-O-galloyl-beta-D-glucose (PGG).
Extracts from Epilobium sp. Herbs, Their Components and Gut Microbiota Metabolites of Epilobium Ellagitannins, Urolithins, Inhibit Hormone‐Dependent Prostate Cancer Cells‐(LNCaP) Proliferation and
TLDR
Results of the work offer an explanation of the activity of Epilobium extracts and support the use of EpILobium preparations in the treatment of prostate diseases.
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