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Expression of tissue factor and tissue factor pathway inhibitor in rats lungs with lipopolysaccharide-induced disseminated intravascular coagulation.
- S. Hara, Y. Asada, +4 authors A. Sumiyoshi
- Laboratory investigation; a journal of technical…
- 1 December 1997
Disseminated intravascular coagulation (DIC) is a frequent complication of endotoxin shock, and modulation of endothelial cell hemostatic properties has been proposed to play an important role in its… Expand
Magnetic Resonance Imaging of Bone Marrow Changes after Irradiation
- H. Sugimura, A. Kisanuki, S. Tamura, Yasushi Kihara, A. Sumiyoshi
- Investigative radiology
- 1 January 1994
RATIONALE AND OBJECTIVESSignal changes of irradiated bone marrow are thought to represent fatty change. However, more recent studies have indicated that other factors may contribute to these signal… Expand
Novel distribution of adrenomedullin-immunoreactive cells in human tissues
- Y. Asada, S. Hara, +7 authors A. Sumiyoshi
- Medicine, Biology
- Histochemistry and Cell Biology
- 1 September 1999
Abstract Adrenomedullin (AM) is a novel hypotensive and vasodilator peptide. We previously examined the localization of AM in human, rat, and porcine tissues using a polyclonal antibody against… Expand
Fibrin-rich and platelet-rich thrombus formation on neointima: recombinant tissue factor pathway inhibitor prevents fibrin formation and neointimal development following repeated balloon injury of…
Thrombus formation and neointimal growth are the critical events in restenosis after balloon angioplasty. However, the responses of diseased vessels to injuries caused by balloon angioplasty have not… Expand
Inhibitory effects of prostacyclin analogue, TFC-132, on aortic neointimal thickening in vivo and smooth muscle cell proliferation in vitro.
- Y. Asada, A. Kisanuki, +4 authors A. Sumiyoshi
- Biology, Medicine
- Prostaglandins, leukotrienes, and essential fatty…
- 1 October 1994
Effects of a new prostacyclin analogue, TFC-132, on neointimal thickening following intimal mechanical injury and on the proliferation of cultured aortic smooth muscle cells (SMCs) were studied. The… Expand
Contribution of the endothelium to intimal thickening in normocholesterolemic and hypercholesterolemic rabbits.
- A. Kisanuki, Y. Asada, K. Hatakeyama, T. Hayashi, A. Sumiyoshi
- Biology, Medicine
- Arteriosclerosis and thrombosis : a journal of…
- 1 October 1992
Endothelial cell injury is considered to be a primary event in the pathogenesis of atherosclerosis. In this study, we investigated the aortic intimal lesion after balloon catheterization in… Expand
Aortic endothelial cell damage induced by β-VLDL and macrophages in vitro
Abstract We performed an in vitro study to assess damage to swine aortic endothelial cells by rabbit β-VLDL and/or rabbit peritoneal macrophages. Incubation of cultured aortic endothelial cells with… Expand
Pulmonary microthromboembolism by injection of sonicated autologous blood in rabbits with splenic artery ligations.
- S. Kietthubthew, A. Kisanuki, Y. Asada, K. Marutsuka, Y. Funahara, A. Sumiyoshi
- The Southeast Asian journal of tropical medicine…
Chronic pulmonary thromboembolism (PTE) has been reported to play an important role in cardiac failure in thalassemic patients after splenectomy. However, the mechanism of PTE in these patients… Expand
Three Cases of Malignant Melanoma Arising on Burn Scars
- H. Kikuchi, T. Nishida, M. Kurokawa, M. Setoyama, A. Kisanuki
- The Journal of dermatology
- 1 August 2003
It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumors. Most of them are squamous cell carcinoma (SCC) and, more occasionally, basal cell carcinoma (BCC). The… Expand
The role of tissue factor in the pathogenesis of thrombosis and atherosclerosis.
- Y. Asada, K. Marutsuka, +4 authors A. Sumiyoshi
- Journal of atherosclerosis and thrombosis
TF is a major regulator of coagulation and hemostasis. High levels of TF antigen and activity are detected in atherosclerotic lesions, particularly in the advanced lesions. When the plaques are… Expand