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Functional Discovery via a Compendium of Expression Profiles
Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental problem in biology. Here, we describe how a single assay can be used to monitor hundreds of different cellularExpand
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Leptospiral Outer Membrane Protein LipL41 Is Not Essential for Acute Leptospirosis but Requires a Small Chaperone Protein, Lep, for Stable Expression
ABSTRACT Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp., but knowledge of leptospiral pathogenesis remains limited. However, the development of mutagenesis systems hasExpand
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Use of Luminescent Leptospira interrogans for Enumeration in Biological Assays
ABSTRACT Rapid and reliable in vitro methods for the detection of pathogenic leptospires, such as Leptospira interrogans, are lacking. The present study investigated the use of luminescence toExpand
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High-Temperature Protein G Is an Essential Virulence Factor of Leptospira interrogans
ABSTRACT Leptospira interrogans is a global zoonotic pathogen and is the causative agent of leptospirosis, an endemic disease of humans and animals worldwide. There is limited understanding ofExpand
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Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.
Clostridium difficile (C. difficile) is a problematic Gram positive bacterial pathogen causing moderate to severe gastrointestinal infections. Based on a lead binaphthyl-tripeptide dicationicExpand
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Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics.
Thirty two new binaphthyl-based, functionalized oxazole and thiazole peptidomimetics and over thirty five novel leucine-containing intermediate oxazoles and thiazoles were prepared in this study.Expand
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Bloom: The Botanical Vernacular in the English Novel
Starting from the botanical crazes inspired by Linnaeus in the eighteenth century, and exploring the variations it spawned - natural history, landscape architecture, polemical battles over botany'sExpand
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Tide Pools
40 Works Cited Collie, J. Norman. Climbing on the Himalaya and Other Mountain Ranges. Edinburgh: David Douglas, 1902. Print. Dent, Clinton Thomas. Above the Snow Line: Mountaineering Sketches betweenExpand
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Reorienting the Scientific Frontier: Victorian Tide Pools and Literary Realism
A hundred times might you fancy you saw the type, the very original of this description, tracing line by line, and image by image, the details of the picture; and acknowledging, as you proceed, theExpand
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