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Early predictors of glucocorticosteroid treatment failure in severe and moderately severe attacks of ulcerative colitis
Objective To analyse the ability of simple clinical and biochemical parameters to predict glucocorticosteroid (GCS) treatment failure in patients with acute attacks of ulcerative colitis.Expand
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Discontinuation of proton pump inhibitors in patients on long‐term therapy: a double‐blind, placebo‐controlled trial
The proportion of proton pump inhibitor users on long‐term therapy who can discontinue proton pump inhibitor (PPI) medication without developing symptoms is unknown.
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Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the
Expression of the adhesion molecules CD44, L-selectin (CD62L), and integrin alpha 4 beta 7 by antibody-secreting cells (ASC) was examined in human volunteers after oral, rectal, intranasal, orExpand
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Health-related quality of life is impaired in active collagenous colitis.
OBJECTIVES The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impactExpand
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Defining clinical criteria for clinical remission and disease activity in collagenous colitis
Background: Collagenous colitis is a chronic inflammatory bowel disease accompanied mainly by nonbloody diarrhea. The objectives of treatment are to alleviate the symptoms and minimize theExpand
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Value of serologic markers for clinical diagnosis and population studies of coeliac disease.
BACKGROUND There is a need for serologic markers in selecting patients with symptoms compatible with coeliac disease for intestinal biopsy and for population screening. Few comparative studies haveExpand
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CA 19-9 and CEA are unreliable markers for cholangiocarcinoma in patients with primary sclerosing cholangitis.
AIMS/BACKGROUND Diagnosis of early cholangiocarcinoma (CC) in patients with primary sclerosing cholangitis with available radiological methods is very difficult. This type of tumor is the second mostExpand
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Celiac disease and other autoimmune diseases in patients with collagenous colitis
Abstract Background and aims. Collagenous colitis (CC) is associated with autoimmune disorders. The aim of the present study was to investigate the relationship between CC and autoimmune disorders inExpand
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Impact of bile acid malabsorption on steatorrhoea and symptoms in patients with chronic diarrhoea
Objective Bile acids are important for fat absorption. The relationship between bile acid malabsorption and steatorrhoea and gastrointestinal symptoms in patients with chronic diarrhoea has only beenExpand
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Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory.
We have examined secretory antibody and cell-mediated immune responses to oral cholera vaccine in the human gastrointestinal mucosa. Freshly isolated peripheral blood lymphocytes and intestinalExpand
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