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Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium.
TLDR
Sutureless transplantation of carrier-free cell sheets composed of autologous oral mucosal epithelial cells may be used to reconstruct corneal surfaces and can restore vision in patients with bilateral severe disorders of the ocular surface. Expand
Ultrathin poly(N-isopropylacrylamide) grafted layer on polystyrene surfaces for cell adhesion/detachment control.
TLDR
PipAAm graft amounts, that is, thickness of the PIPAAm grafted layers, play a crucial role in temperature-induced hydrophilic/hydrophobic property alterations and cell adhesion/detachment behavior. Expand
Fabrication of Pulsatile Cardiac Tissue Grafts Using a Novel 3-Dimensional Cell Sheet Manipulation Technique and Temperature-Responsive Cell Culture Surfaces
TLDR
These results demonstrate that electrically communicative pulsatile 3-D cardiac constructs were achieved both in vitro and in vivo by layering cardiomyocyte sheets. Expand
Cell sheet engineering for myocardial tissue reconstruction.
TLDR
Novel tissue engineering methodology layering cell sheets to construct 3-D functional tissues without any artificial scaffolds is proposed and should have enormous potential for fabricating clinically applicable myocardial tissues and should promote tissue engineering research fields. Expand
Preparation of thermoresponsive polymer brush surfaces and their interaction with cells.
TLDR
Thermoresponsive surfaces prepared by surface-initiated ATRP techniques allow surface selection in preparing cell sheets from attachment-dependent cells having relatively strong adhesive property for tissue engineering applications. Expand
Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues
TLDR
C cultured cell sheet integration methods overcome long‐standing barriers to producing thick, vascularized tissues, revealing a possible solution for the clinical repair of various damaged organs, including the impaired myocardium. Expand
Pulsatile drug release control using hydrogels.
TLDR
Several types of drug delivery systems using hydrogels are discussed that showed pulsed and/or pulsatile drug delivery characteristics and thermal stimuli-regulated pulsed drug release is established through the design of drug Delivery devices, hydrogel, and micelles. Expand
Functional human corneal endothelial cell sheets harvested from temperature‐responsive culture surfaces
TLDR
The results support the value of harvested cell sheets for clinical applications in ocular reconstructive surgery in patients with ocular endothelial decompensation and establish a regimen to culture and proliferate human corneal endothelial cells and fabricate endothelial sheets ex vivo morphologically and functionally similar to the native corneals. Expand
Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfaces.
TLDR
Temperature-responsive surfaces can provide a novel method to use cultured confluent cell sheets for tissue engineering, and also to elucidate structure and function of deposited extracellular matrix during cell culture. Expand
Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model.
TLDR
The results suggest that this technique, based on the concept of cell sheet engineering, can be useful for periodontal tissue regeneration. Expand
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