• Publications
  • Influence
Isolated Loss of PMS2 Immunohistochemical Expression is Frequently Caused by Heterogenous MLH1 Promoter Hypermethylation in Lynch Syndrome Screening for Endometrial Cancer Patients
Lynch syndrome (LS) is an autosomal-dominant inherited disorder mainly caused by a germline mutation in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) and is associated withExpand
  • 20
  • 2
Uniqueness of ductal carcinoma in situ of the breast concurrent with papilloma: implications from a detailed topographical and histopathological study of 50 cases treated by mastectomy and wide local
To clarify the diagnostic clues of ductal carcinomas in situ (DCIS) associated with papilloma and optimal clinical management of papilloma diagnosed on core needle biopsy (CNB).
  • 8
  • 1
Mammalian olfactory receptors: pharmacology, G protein coupling and desensitization
  • A. Kato, K. Touhara
  • Medicine, Biology
  • Cellular and Molecular Life Sciences
  • 4 August 2009
The vertebrate olfactory system recognizes and discriminates between thousands of structurally diverse odorants. Detection of odorants in mammals is mediated by olfactory receptors (ORs), whichExpand
  • 70
  • 1
Amino acids involved in conformational dynamics and G protein coupling of an odorant receptor: targeting gain‐of‐function mutation
Thousands of different odorants are recognized and discriminated by odorant receptors (ORs) in the guanine nucleotide‐binding protein (G protein)‐coupled seven‐transmembrane receptor family.Expand
  • 31
  • 1
Relative Role of Flower Color and Scent on Pollinator Attraction: Experimental Tests using F1 and F2 Hybrids of Daylily and Nightlily
The daylily (Hemerocallis fulva) and nightlily (H. citrina) are typical examples of a butterfly-pollination system and a hawkmoth-pollination system, respectively. H. fulva has diurnal, reddish orExpand
  • 38
  • 1
Efficient screening strategy for Lynch syndrome in Japanese endometrial cancer.
Lynch syndrome (LS) is an inherited disorder caused by a germline mutation in the DNA mismatch repair (MMR) genes and is associated with increased risk of various cancers, particularly colorectalExpand
  • 8
  • 1
Topographical, morphological and immunohistochemical characteristics of carcinoma in situ of the breast involving sclerosing adenosis. Two distinct topographical patterns and histological types of
Moritani S, Ichihara S, Hasegawa M, Endo T, Oiwa M, Shiraiwa M, Nishida C, Morita T, Sato Y, Hayashi T, Kato A, Aoyama H & Yoshikawa K
(2011) Histopathology 58, 835–846
Topographical, morphologicalExpand
  • 15
  • 1
Clinical characteristics of Lynch-like cases collaterally classified by Lynch syndrome identification strategy using universal screening in endometrial cancer.
OBJECTIVE Lynch syndrome (LS), an autosomal-dominant inherited disorder, increases the risk for LS-associated cancers (LS-AC). Molecular LS assessment for all cases is referred to as universalExpand
  • 9
  • 1
Intracytoplasmic Lipid Accumulation in Apocrine Carcinoma of the Breast Evaluated With Adipophilin Immunoreactivity: A Possible Link Between Apocrine Carcinoma and Lipid-rich Carcinoma
Although apocrine carcinoma is a distinct histologic entity, there is no immunohistochemical marker to confirm apocrine differentiation with high sensitivity and specificity, and its differentialExpand
  • 22
Evaluation of the role of g protein-coupled receptor kinase 3 in desensitization of mouse odorant receptors in a Mammalian cell line and in olfactory sensory neurons.
Thousands of odors are sensed and discriminated by G protein-coupled odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs). G protein-coupled receptor kinases (GRKs) may have a roleExpand
  • 9