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Efficacy and safety of oral alitretinoin (9‐cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double‐blind,
Background  Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studiesExpand
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Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors
Background Tofacitinib is an oral Janus kinase inhibitor that is under investigation for the treatment of psoriatic arthritis. We evaluated tofacitinib in patients with active psoriatic arthritis whoExpand
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Adapalene–benzoyl peroxide, a unique fixed‐dose combination topical gel for the treatment of acne vulgaris: a transatlantic, randomized, double‐blind, controlled study in 1670 patients
Background  Combination therapy utilizing agents with complementary mechanisms of action is recommended by acne guidelines to help simultaneously target multiple pathogenic factors. A unique,Expand
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Diagnostics and treatment of psoriasis vulgaris: guidelines of the Polish Dermatological Society.Part I: mild psoriasis, psoriasis in children
Psoriasis is a chronic inflammatory skin disease affecting about 1-3% of the Caucasian population. Psoriasis is still not a curable disease, however, during the last couple of years rapid progress inExpand
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Impact of psoriasis severity on family income and quality of life
Psoriasis is a common disease and the costs of its therapy, medical care and loss of productivity are a major financial burden for patients and society. The financial status of psoriasis patients andExpand
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In psoriasis, levels of hope and quality of life are linked
Psychological resources such as hope have been suggested to positively influence quality of life (QoL) in chronic disorders. Here, we determined hope levels of psoriasis vulgaris in-patients andExpand
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Efficacy and safety of the freeze‐dried cultured human keratinocyte lysate, LyphoDerm™ 0.9%, in the treatment of hard‐to‐heal venous leg ulcers
LyphoDermTM (XCELLentis, Belgium) is an end‐sterilized, freeze‐dried lysate from cultured allogeneic epidermal keratinocytes, formulated into a hydrophilic gel. Its efficacy and safety wereExpand
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Efficacy of Tofacitinib for the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis in Patient Subgroups from Two Randomised Phase 3 Trials.
BACKGROUND Tofacitinib is a Janus kinase inhibitor being investigated for the treatment of moderate-to-severe plaque psoriasis. We report efficacy of tofacitinib in patient subgroups based on pooledExpand
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Role of primary and secondary prevention in atopic dermatitis
Atopic dermatitis (AD) is a serious epidemiological problem in industrialized countries. The incidence of AD has increased considerably over the last 30 years. Atopic dermatitis is a chronic,Expand
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The antibacterial activity of geranium oil against Gram-negative bacteria isolated from difficult-to-heal wounds.
Hard-to-heal wounds represent a significant problem to patients, health care professionals, and health care system. They can be formed as a result of mechanical injuries and burns, and anyExpand
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