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Clinical review: The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis.
TLDR
The present review summarizes the evidence on the potential role of cortisol in the pathogenesis of MetS and discusses new therapeutic approaches for patients with MetS, which may be partly associated with chronic stress and/or low birth weight.
Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease
TLDR
Statin treatment is safe and can improve liver tests and reduce cardiovascular morbidity in patients with mild-to-moderately abnormal liver tests that are potentially attributable to non-alcoholic fatty liver disease.
Gonadal dysfunction in systemic diseases.
TLDR
A brief review of the most common disturbances seen in the main systemic diseases of gonadal dysfunction will be discussed.
Pheochromocytoma: an update on genetics and management.
TLDR
The genetics, the pathophysiology of hypertension, the clinical picture, the biochemical and imaging diagnosis, and the preferred therapeutic approach for PGLs/PHEOs are discussed.
Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study
TLDR
Multifactorial intervention in MetS patients with both biochemical and ultrasonographic evidence ofNAFLD offsets surrogate markers of NAFLD (i.e. elevated aminotransferase plus echogenic liver).
Cardiovascular risk across the histological spectrum and the clinical manifestations of non-alcoholic fatty liver disease: An update.
TLDR
Lifestyle measures and statin treatment may help resolve NAFLD/NASH and beneficially affect the CVD risk factors mentioned above.
Comparison of four definitions of the metabolic syndrome in a Greek (Mediterranean) population
TLDR
When diagnosed according to the new JIS definition, the prevalence of MetS was high in a Greek Mediterranean cohort (nearly half of the adult population) and the NCEP-ATP-III and AHA/NHLBI definitions were more predictive of CVD risk than the newJIS definition.
Effect of tobacco smoking and smoking cessation on plasma lipoproteins and associated major cardiovascular risk factors: a narrative review
TLDR
This narrative review considers the relationship between cigarette smoking and CVD, and discusses disease states and/or CVD risk factors related to smoking, such as dyslipidaemia, vascular inflammation, endothelial dysfunction, arterial stiffness, insulin resistance, type 2 diabetes mellitus, and non-alcoholic fatty liver disease as well as their complex interrelations.
Should adipokines be considered in the choice of the treatment of obesity-related health problems?
TLDR
Treatment options for the normalisation of adipokine levels are summarised, which might confer an additional clinical benefit in the effort to prevent or treat obesity-related T2DM and CVD.
Serum uric acid as an independent predictor of early death after acute stroke.
TLDR
Elevated levels of SUA are independently associated with an increased risk of early death in acute stroke and are confirmed on multiple logistic regression analysis.
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