A. Kar

Publications150
h-index37
Citations3,866
Highly Influential Citations92
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Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and…
TLDR
Besides antiperoxidative activity, C. sinensis extract has antithyroidal, hypoglycemic, and insulin stimulatory properties, which suggest its potential to ameliorate both hyperthyroidism and diabetes mellitus.
Protective effects of vitamin E against lead-induced deterioration of membrane associated type-I iodothyronine 5'-monodeiodinase (5'D-I) activity in male mice.
Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice.
Apigenin (4‘,5,7‐trihydroxyflavone) regulates hyperglycaemia, thyroid dysfunction and lipid peroxidation in alloxan‐induced diabetic mice
  • S. Panda, A. Kar
  • Biology, Medicine
    The Journal of pharmacy and pharmacology
  • 1 November 2007
TLDR
It appears that apigenin has a potential to regulate diabetes mellitus, as well as disease‐induced thyroid dysfunction and lipid peroxidation, and its hepatoprotective potential is suggested.
Role of ascorbic acid in cadmium‐induced thyroid dysfunction and lipid peroxidation
TLDR
It appears that the protective effect of AA against cadmium‐induced thyroid dysfunction is mediated through its antioxidative action.
Cardioprotective potential of N,α-L-rhamnopyranosyl vincosamide, an indole alkaloid, isolated from the leaves of Moringa oleifera in isoproterenol induced cardiotoxic rats: in vivo and in vitro…
Evaluation of the antithyroid, antioxidative and antihyperglycemic activity of scopoletin from Aegle marmelos leaves in hyperthyroid rats
  • S. Panda, A. Kar
  • Medicine, Biology
    Phytotherapy research : PTR
  • 1 December 2006
TLDR
Findings indicate that scopoletin has the potential to inhibit thyroid function and hyperglycemia without hepatotoxicity.
Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice.
Loss of membrane integrity and inhibition of type-I iodothyronine 5'-monodeiodinase activity by fenvalerate in female mouse.
TLDR
A marginal increase in T4 concentration in highest dose-treated group compared to that of the lower one supports the view that the monodeiodination of the phenolic ring of T4 is inhibited by fenvalerate.
Free radical mediated membrane perturbation and inhibition of type‐I iodothyronine 5′‐monodeiodinase activity by lead and cadmium in rat liver homogenate
TLDR
Since LPO is primarily an outcome of free radical generation, it is suggested metal induced free radical mediated inhibition of 5′‐D activity in rat liver homogenate is suggested.
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