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Molecular epidemiology of HIV.
The phylogenic analysis of the nucleotide sequences of the env gene has enabled classification of HIV-1 into three groups. The group M of HIV-1 infection has been classified into 9 different geneticExpand
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Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs
Humans are teeming with microbes that comprise our microbiome and contribute to health and disease. A typical human with 1012 nucleated cells is estimated to have 1015 virions and 1013 bacteria (1,Expand
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Inferring Viral Dynamics in Chronically HCV Infected Patients from the Spatial Distribution of Infected Hepatocytes
Chronic liver infection by hepatitis C virus (HCV) is a major public health concern. Despite partly successful treatment options, several aspects of intrahepatic HCV infection dynamics are stillExpand
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Drug resistant mutations detected by genotypic drug resistance testing in patients failing therapy in clade C HIV-1 infected individuals from India.
PURPOSE There has been an increase in the number of individuals administered antiretroviral therapy (ART) in India but treatment outcome is hampered by increasing development of drug resistance.Expand
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Usefulness of Alternate Prognostic Serum and Plasma Markers for Antiretroviral Therapy for Human Immunodeficiency Virus Type 1 Infection
ABSTRACT In developing countries, the usability of peripheral blood constituents that are low-cost alternatives to CD4-positive (CD4+) T-cell and human immunodeficiency virus type 1 (HIV-1) RNAExpand
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The frequency of HIV-I drug resistance mutations among treatment-naïve individuals at a tertiary care centre in south India
Antiretroviral treatment (ART) use in India requires information on baseline drug resistance mutations and polymorphisms in the protease (Pr) and reverse transcriptase (RT) genes of HIV-1 strainsExpand
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High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.
OBJECTIVES To determine the rates, reasons and predictors of treatment change of the initial antiretroviral treatment (ART) regimen in HIV-infected south Indian adults. METHODS In this prospectiveExpand
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Comparison of two methods to detect carbapenemase & metallo-beta- lactamase production in clinical isolates.
BACKGROUND & OBJECTIVE Bacterial resistance has greatly hampered effective treatment of patients in clinical settings. Non-fermenting Gram-negative bacilli (NFGNB) are common nosocomial pathogens. InExpand
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Comparison of Microcapillary Cytometry Technology and Flow Cytometry for CD4+ and CD8+ T-Cell Estimation
ABSTRACT An alternative technology for the estimation of T cells based on a microcapillary technique (Guava Technologies, Hayward, CA) was compared to FACSCount (Becton Dickinson, San Jose, CA).Expand
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Changes in Hospital – Physician Affiliations in U . S . Hospitals
TO THE EDITOR: I read Scott and colleagues' (1) article with interest. I am an internist in a small private group founded in our community more than 30 years ago. Our practice will soon becomeExpand
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