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Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats
Permanent middle cerebral artery occlusion (MCAO) causes neuronal cell death in the striatum and cortex. In rodents, estradiol treatment protects the cortex from cell death in an estrogen receptor… Expand
Changes in estrogen receptor-alpha mRNA in the mouse cortex during development
Estrogen plays a critical role in brain development and is responsible for generating sex differences in cognition and emotion. Studies in rodent models have shown high levels of estrogen binding in… Expand
Dynamic regulation of estrogen receptor-alpha gene expression in the brain: A role for promoter methylation?
Estrogen has long been known to play an important role in coordinating the neuroendocrine events that control sexual development, sexual behavior and reproduction. Estrogen actions in other,… Expand